New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.
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Molecular mechanisms mediating the G protein-coupled receptor regulation of cell cycle progressionEpac: A new cAMP-binding protein in support of glucagon-like peptide-1 receptor-mediated signal transduction in the pancreatic beta-cellTherapeutic treatments potentially mediated by melatonin receptors: potential clinical uses in the prevention of osteoporosis, cancer and as an adjuvant therapyRenal expression of exchange protein directly activated by cAMP (Epac) 1 and 2Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activationBiasing the prostaglandin F2α receptor responses toward EGFR-dependent transactivation of MAPK.cAMP analogs and their metabolites enhance TREK-1 mRNA and K+ current expression in adrenocortical cells.ACTH induces Cav3.2 current and mRNA by cAMP-dependent and cAMP-independent mechanisms.Evidence for a pro-proliferative feedback loop in prostate cancer: the role of Epac1 and COX-2-dependent pathways.Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.Disruption of parathyroid hormone and parathyroid hormone-related peptide receptor phosphorylation prolongs ERK1/2 MAPK activation and enhances c-fos expressionA-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytesPTH(1-84)/PTH(7-84): a balance of power.Na/H exchange regulatory factor 1, a novel AKT-associating protein, regulates extracellular signal-regulated kinase signaling through a B-Raf-mediated pathway.Polycystic kidney disease: genes, proteins, animal models, disease mechanisms and therapeutic opportunities.Constitutive protein kinase A activity in osteocytes and late osteoblasts produces an anabolic effect on boneRas-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.Protein kinase A and C regulate leak potassium currents in freshly isolated vascular myocytes from the aorta.PTH and PTHrP signaling in osteoblastsEPAC proteins transduce diverse cellular actions of cAMP.N6-substituted cAMP analogs inhibit bTREK-1 K+ channels and stimulate cortisol secretion by a protein kinase A-independent mechanism.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.The PTH-Gαs-protein kinase A cascade controls αNAC localization to regulate bone mass.Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.Parathyroid hormone-potentiated connective tissue growth factor expression in human renal proximal tubular cells through activating the MAPK and NF-kappaB signalling pathways.Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells.Prostaglandin E2 activates Rap1 via EP2/EP4 receptors and cAMP-signaling in rheumatoid synovial fibroblasts: involvement of Epac1 and PKA.Prostaglandin E2 inhibits specific lung fibroblast functions via selective actions of PKA and Epac-1.Proline-rich motifs in the parathyroid hormone (PTH)/PTH-related protein receptor C terminus mediate scaffolding of c-Src with beta-arrestin2 for ERK1/2 activation.Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors.Impact of the mitogen-activated protein kinase pathway on parathyroid hormone-related protein actions in osteoblasts.Parathyroid hormone induction of the osteocalcin gene. Requirement for an osteoblast-specific element 1 sequence in the promoter and involvement of multiple-signaling pathways.Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.Involvement of cAMP response element-binding protein in the regulation of cell proliferation and the prolactin promoter of lactotrophs in primary culture.The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction.PTHrP on MCF-7 breast cancer cells: a growth factor or an antimitogenic peptide?Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells.Differential regulation of mesangial cell mitogenesis by cAMP phosphodiesterase isozymes 3 and 4.Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.
P2860
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P2860
New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
New signaling pathway for para ...... t of modulation by cyclic AMP.
@en
type
label
New signaling pathway for para ...... t of modulation by cyclic AMP.
@en
prefLabel
New signaling pathway for para ...... t of modulation by cyclic AMP.
@en
P2093
P2860
P356
P1476
New signaling pathway for para ...... t of modulation by cyclic AMP.
@en
P2093
Hiromichi Nakamuta
Masao Koida
Ryo Fukuyama
Takashi Fujita
Toru Meguro
P2860
P304
22191-22200
P356
10.1074/JBC.M110364200
P407
P577
2002-04-15T00:00:00Z