Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.
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UVA-induced cell cycle progression is mediated by a disintegrin and metalloprotease/epidermal growth factor receptor/AKT/Cyclin D1 pathways in keratinocytesTransforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumabVisualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.Administration of ricin induces a severe inflammatory response via nonredundant stimulation of ERK, JNK, and P38 MAPK and provides a mouse model of hemolytic uremic syndrome.Protein secretion in human mammary epithelial cells following HER1 receptor activation: influence of HER2 and HER3 expression.Metalloproteinase-dependent cleavage of neuregulin and autocrine stimulation of vascular endothelial cells.Molecular and cellular characterization of Neuregulin-1 type IV isoforms.Long-range signal transmission in autocrine relays.Discrete models of autocrine cell communication in epithelial layersSelf-organization of polarized cell signaling via autocrine circuits: computational model analysis.Multiple mechanisms are responsible for transactivation of the epidermal growth factor receptor in mammary epithelial cells.Multiple personalities of neuregulin gene family members.Evolutionary dynamism of the primate LRRC37 gene family.ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding.Fibrinogen binding to ICAM-1 promotes EGFR-dependent mucin production in human airway epithelial cells.Ribosomal alteration-derived signals for cytokine induction in mucosal and systemic inflammation: noncanonical pathways by ribosomal inactivation.Role of proneuregulin 1 cleavage and human epidermal growth factor receptor activation in hypertonic aquaporin induction.Sequential proteolytic processing of an interferon-alpha receptor subunit by TNF-alpha converting enzyme and presenilins.Endogenous expression of Neuregulin-1 (Nrg1) as a potential modulator of prolactin (PRL) secretion in GH3 cells.The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9.Loss of ectodomain shedding due to mutations in the metalloprotease and cysteine-rich/disintegrin domains of the tumor necrosis factor-alpha converting enzyme (TACE).Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide.Stimulated shedding of vascular cell adhesion molecule 1 (VCAM-1) is mediated by tumor necrosis factor-alpha-converting enzyme (ADAM 17).Signal propagation and failure in discrete autocrine relays.The immunoglobulin-like domain of neuregulins potentiates ErbB3/HER3 activation and cellular proliferation.
P2860
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P2860
Mitogen-activated protein kinase-dependent and -independent routes control shedding of transmembrane growth factors through multiple secretases.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mitogen-activated protein kina ...... s through multiple secretases.
@en
type
label
Mitogen-activated protein kina ...... s through multiple secretases.
@en
prefLabel
Mitogen-activated protein kina ...... s through multiple secretases.
@en
P2860
P50
P1433
P1476
Mitogen-activated protein kina ...... rs through multiple secretases
@en
P2093
Atanasio Pandiella
Laura Yuste
P2860
P304
P356
10.1042/0264-6021:3630211
P407
P577
2002-04-01T00:00:00Z