PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells. - Wikidata - awgldk - TriplyDB

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.

http://www.wikidata.org/entity/Q40743174

about

Upregulation of the mammalian target of rapamycin complex 1 pathway by Ras homolog enriched in brain in pancreatic beta-cells leads to increased beta-cell mass and prevention of hyperglycemia Overexpression of KLF15 transcription factor in adipocytes of mice results in down-regulation of SCD1 protein expression in adipocytes and consequent enhancement of glucose-induced insulin secretion Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance Expression and localization of mesothelin in developing rat pancreas Spatial regulation of VEGF receptor endocytosis in angiogenesis CaV2.3 channel and PKClambda: new players in insulin secretion Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1 Contribution of protein kinase Cα in the stimulation of insulin by the down-regulation of Cavβ subunits.Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes.Ras-related C3 botulinum toxin substrate 1 (RAC1) regulates glucose-stimulated insulin secretion via modulation of F-actin.Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes.Genome-wide association study of colorectal cancer in Hispanics.Metabolic functions of atypical protein kinase C: "good" and "bad" as defined by nutritional status.Of the atypical PKCs, Par-4 and p62: recent understandings of the biology and pathology of a PB1-dominated complex.Epidermal polarity genes in health and disease Autocrine Signaling Underlies Fast Repetitive Plasma Membrane Translocation of Conventional and Novel Protein Kinase C Isoforms in β Cells.Congenital hyperinsulinism caused by hexokinase I expression or glucokinase-activating mutation in a subset of β-cells.Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice.Ablation of C/EBPbeta alleviates ER stress and pancreatic beta cell failure through the GRP78 chaperone in mice.Role of iduronate-2-sulfatase in glucose-stimulated insulin secretion by activation of exocytosis.A toxicogenomics approach to identify new plausible epigenetic mechanisms of ochratoxin a carcinogenicity in rat.Genetic dissection of the Nrf2-dependent redox signaling-regulated transcriptional programs of cell proliferation and cytoprotection.Regulation of insulin exocytosis by calcium-dependent protein kinase C in beta cells.

P2860

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P2860

PKClambda regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic beta cells.

http://www.wikidata.org/entity/Q40743174

description

2005 nî lūn-bûn

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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2005年论文

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2005年论文

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name

PKClambda regulates glucose-in ...... sion in pancreatic beta cells.

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PKClambda regulates glucose-in ...... sion in pancreatic beta cells.

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PKClambda regulates glucose-in ...... sion in pancreatic beta cells.

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P1433

Journal of Clinical Investigation

P1476

PKClambda regulates glucose-in ...... sion in pancreatic beta cells.

@en

P2093

Hiroaki Fujihara

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Hiroshi Inoue

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Kazuhisa Suzuki

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Kazunori Akimoto

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Masato Kasuga

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Michihiro Matsumoto

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Naoko Hashimoto

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Sakan Maeda

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Shigeo Ohno

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Tetsuo Noda

http://www.w3.org/2001/XMLSchema#string

P2860

Requirement of atypical protein kinase clambda for insulin stimulation of glucose uptake but not for Akt activation in 3T3-L1 adipocytes

Atypical protein kinase C is involved in the evolutionarily conserved par protein complex and plays a critical role in establishing epithelia-specific junctional structures

Molecular cloning and characterization of PKC iota, an atypical isoform of protein kinase C derived from insulin-secreting cells

Protein kinase C lambda/iota (PKClambda/iota): a PKC isotype essential for the development of multicellular organisms

Early diabetes and abnormal postnatal pancreatic islet development in mice lacking Glut-2

Tissue-specific deletion of Foxa2 in pancreatic beta cells results in hyperinsulinemic hypoglycemia

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase

Foxa2 (HNF3beta ) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release

Effects of mutations in the insulin-like growth factor signaling system on embryonic pancreas development and beta-cell compensation to insulin resistance

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138-145

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scholarly article

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10.1172/JCI22232

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1

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115

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15630453

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539193

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