Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein-Barr virus potential through both culture-dependent and selection process-dependent mechanisms.
about
A new direction for gene therapy: intrathymic T cell-specific lentiviral gene transfer.Recognition of fresh human tumor by human peripheral blood lymphocytes transduced with a bicistronic retroviral vector encoding a murine anti-p53 TCR.Longitudinal, noninvasive imaging of T-cell effector function and proliferation in living subjects.Genetically modified donor leukocyte transfusion and graft-versus-leukemia effect after allogeneic stem cell transplantation.Genetic control of wayward pluripotent stem cells and their progeny after transplantation.Analysis of transgene-specific immune responses that limit the in vivo persistence of adoptively transferred HSV-TK-modified donor T cells after allogeneic hematopoietic cell transplantation.Clinical-scale lentiviral vector transduction of PBL for TCR gene therapy and potential for expression in less-differentiated cells.Adoptive T-cell transfer in cancer immunotherapy.T-cell receptor gene transfer by lentiviral vectors in adoptive cell therapy.Genetic modification of T cells for immunotherapy.Development of optimal bicistronic lentiviral vectors facilitates high-level TCR gene expression and robust tumor cell recognitionNovel application of lentiviral vectors towards treatment of graft-versus-host disease.Suicide gene therapy for graft-versus-host disease.Immunotherapy against EBV-lymphoma in recipients of HSCT.Gene-modified T lymphocytes in the setting of hematopoietic cell transplantation: potential benefits and possible risks.Ex vivo gene transfer and correction for cell-based therapies.OuaSelect, a novel ouabain-resistant human marker gene that allows efficient cell selection within 48 h.Stable gene transfer and expression in human primary T cells by the Sleeping Beauty transposon system.Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation.Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation.An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies.A novel 'sort-suicide' fusion gene vector for T cell manipulation.Kinetics of cell death in T lymphocytes genetically modified with two novel suicide fusion genes.Functional impairment of human T-lymphocytes following PHA-induced expansion and retroviral transduction: implications for gene therapy.Gamma-glutamylcysteine synthetase-based selection strategy for gene therapy of chronic granulomatous disease and graft-vs.-host disease.Functional and phenotypic variations in human T cells subjected to retroviral-mediated gene transfer.Preferential retroviral-mediated transduction of EBV- and CMV-specific T cells after polyclonal T-cell activation.Exposure to hypomethylating agent, 5-azacytidine, may improve iCasp9 suicide gene therapy for treating GvHD in allografts.Regulatory T-cell expansion and function do not account for the impaired alloreactivity of ex vivo-expanded T cells.
P2860
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P2860
Retrovirus-mediated gene transfer in primary T lymphocytes impairs their anti-Epstein-Barr virus potential through both culture-dependent and selection process-dependent mechanisms.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Retrovirus-mediated gene trans ...... process-dependent mechanisms.
@en
type
label
Retrovirus-mediated gene trans ...... process-dependent mechanisms.
@en
prefLabel
Retrovirus-mediated gene trans ...... process-dependent mechanisms.
@en
P2093
P356
P1433
P1476
Retrovirus-mediated gene trans ...... n process-dependent mechanisms
@en
P2093
Anne Duperrier
Bruno Petracca
Christophe Ferrand
Eric Robinet
François Lang
Jane F Apperley
Junia V Melo
Marie Bodinier
Nicolas Tonnelier
Patrick Hervé
P304
P356
10.1182/BLOOD.V99.4.1165
P407
P577
2002-02-01T00:00:00Z