β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
about
Overexpression, purification, and functional analysis of recombinant human tubulin dimerThe axonal cytoskeleton: from organization to functionGenetic analysis of a novel tubulin mutation that redirects synaptic vesicle targeting and causes neurite degeneration in C. elegansReversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interface.Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdownThe intricate relationship between microtubules and their associated motor proteins during axon growth and maintenance.Multiple-pulse pumping for enhanced fluorescence detection and molecular imaging in tissue.Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.The tubulin code: molecular components, readout mechanisms, and functionsAxonal transport rate decreased at the onset of optic neuritis in EAE miceHeavy ion and X-ray irradiation alter the cytoskeleton and cytomechanics of cortical neurons.The marriage of quantitative genetics and cell biology: a novel screening approach reveals people have genetically encoded variation in microtubule stability.Neuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucomaHypomyelination with atrophy of the basal ganglia and cerebellum: further delineation of the phenotype and genotype-phenotype correlation.Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3.A mutation in the Tubb4a gene leads to microtubule accumulation with hypomyelination and demyelination.Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-Ends.Branch-Specific Microtubule Destabilization Mediates Axon Branch Loss during Neuromuscular Synapse Elimination.Microtubule Destabilization Paves the Way to Parkinson's Disease.Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance.Leukodystrophies: a proposed classification system based on pathological changes and pathogenetic mechanisms.An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy ResistanceAnalyzing kinesin motor domain translocation in cultured hippocampal neurons.Off the rails: axonal cargoes on the road to nowhere.Microtubule Organization Determines Axonal Transport Dynamics.Tau and spectraplakins promote synapse formation and maintenance through Jun kinase and neuronal trafficking.Hippocampal to basal forebrain transport of Mn2+ is impaired by deletion of KLC1, a subunit of the conventional kinesin microtubule-based motor.Elevated copper ion levels as potential cause of impaired kinesin-dependent transport processes.Common general anesthetic propofol impairs kinesin processivity.Postmortem Diagnostic Exome Sequencing Identifies a De Novo TUBB3 Alteration in a Newborn With Prenatally Diagnosed Hydrocephalus and Suspected Walker-Warburg Syndrome.Bipolar disorder in youth is associated with increased levels of vitamin D-binding protein.BORC Regulates the Axonal Transport of Synaptic Vesicle Precursors by Activating ARL-8.Tubulin and Tau: Possible targets for diagnosis of Parkinson's and Alzheimer's diseases.Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration
P2860
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P2860
β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
@en
type
label
β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
@en
prefLabel
β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
@en
P2093
P2860
P356
P1433
P1476
β-Tubulin mutations that cause severe neuropathies disrupt axonal transport.
@en
P2093
Hironori Takahashi
Nobutaka Hirokawa
Shinsuke Niwa
P2860
P304
P356
10.1038/EMBOJ.2013.59
P407
P577
2013-03-15T00:00:00Z