Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy
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A Phase I study of the angiogenesis inhibitor SU5416 (semaxanib) in solid tumours, incorporating dynamic contrast MR pharmacodynamic end pointsBenefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitorsHeparin in malignant glioma: review of preclinical studies and clinical resultsMatrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesisHedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish.Intravital fluorescence videomicroscopy to study tumor angiogenesis and microcirculationAntitumor activity of cytotoxic T lymphocytes engineered to target vascular endothelial growth factor receptors.Imaging of VEGF receptor kinase inhibitor-induced antiangiogenic effects in drug-resistant human adenocarcinoma model.Clinical experience with angiogenesis signaling inhibitors: focus on vascular endothelial growth factor (VEGF) blockers.Influence of soluble or matrix-bound isoforms of vascular endothelial growth factor-A on tumor response to vascular-targeted strategies.Vascular endothelial growth factor receptor inhibitor SU5416 suppresses lymphocyte generation and immune responses in mice by increasing plasma corticosterone.Advances in molecular therapies in patients with brain tumors.Novel therapies for patients with chronic myeloid leukemia.MRI for assessing antivascular cancer treatments.Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation.Bevacizumab in the management of solid tumors.Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice.Antiangiogenic therapy in brain tumors.An update in the use of antibodies to treat glioblastoma multiforme.A critical analysis of current in vitro and in vivo angiogenesis assays.Control of the blood-brain barrier function in cancer cell metastasis.Role of plasma membrane caveolae/lipid rafts in VEGF-induced redox signaling in human leukemia cells.Orthogonal polarisation spectral imaging as a new tool for the assessment of antivascular tumour treatment in vivo: a validation study.Improved effect of an antiangiogenic tyrosine kinase inhibitor (SU5416) by combinations with fractionated radiotherapy or low molecular weight heparinVEGF activates NR2B phosphorylation through Dab1 pathway.Differential expression of protein tyrosine kinase genes during microglial activation.Contrast-assisted destruction-replenishment ultrasound for the assessment of tumor microvasculature in a rat model.Pharmacokinetics and interspecies scaling of a novel VEGF receptor inhibitor, SU5416.The microcirculation in acute murine cutaneous incisional wounds shows a spatial and temporal variation in the functionality of vessels.Intravital microscopy in the study of the tumor microenvironment: from bench to human application.Targeting the extradomain A of fibronectin allows identification of vascular resistance to antiangiogenic therapy in experimental glioma.Targeting angiogenesis inhibits tumor infiltration and expression of the pro-invasive protein SPARC.
P2860
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P2860
Inhibition of tumor growth, angiogenesis, and microcirculation by the novel Flk-1 inhibitor SU5416 as assessed by intravital multi-fluorescence videomicroscopy
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Inhibition of tumor growth, an ...... i-fluorescence videomicroscopy
@en
type
label
Inhibition of tumor growth, an ...... i-fluorescence videomicroscopy
@en
prefLabel
Inhibition of tumor growth, an ...... i-fluorescence videomicroscopy
@en
P2093
P2860
P356
P1433
P1476
Inhibition of tumor growth, an ...... i-fluorescence videomicroscopy
@en
P2093
Schilling L
Schmiedek P
Vajkoczy P
P2860
P356
10.1038/SJ.NEO.7900006
P577
1999-04-01T00:00:00Z