Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.
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Apoptosis in pancreatic β-islet cells in Type 2 diabetesRoles of Pyruvate, NADH, and Mitochondrial Complex I in Redox Balance and Imbalance in β Cell Function and DysfunctionThe malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cellsFeasibility of pathways for transfer of acyl groups from mitochondria to the cytosol to form short chain acyl-CoAs in the pancreatic beta cellMitochondrial GTP regulates glucose-stimulated insulin secretionDual role of proapoptotic BAD in insulin secretion and beta cell survivalPlasma membrane potential oscillations in insulin secreting Ins-1 832/13 cells do not require glycolysis and are not initiated by fluctuations in mitochondrial bioenergetics.Rat neonatal beta cells lack the specialised metabolic phenotype of mature beta cells.Glucose sensing in the pancreatic beta cell: a computational systems analysis.Leucine metabolism in regulation of insulin secretion from pancreatic beta cells.Comparative Analysis of the Mitochondrial Physiology of Pancreatic β CellsFunctional mapping of disease susceptibility loci using cell biology.Developmental origins of adult disease.Measurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells.Developmental origins of diabetes: The role of oxidative stressMitochondrial transporters as novel targets for intracellular calcium signaling.The role of rapid lipogenesis in insulin secretion: Insulin secretagogues acutely alter lipid composition of INS-1 832/13 cellsUncoupling proteins: role in insulin resistance and insulin insufficiencyGlucagon-like peptide-1 induced signaling and insulin secretion do not drive fuel and energy metabolism in primary rodent pancreatic beta-cells.CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensorMitochondrial glutamate carrier GC1 as a newly identified player in the control of glucose-stimulated insulin secretion.Oxidative stress: the mitochondria-dependent and mitochondria-independent pathways of apoptosis.Characterization of stimulus-secretion coupling in the human pancreatic EndoC-βH1 beta cell line.The Pancreatic β-Cell: A Bioenergetic Perspective.Fuel-Stimulated Insulin Secretion Depends upon Mitochondria Activation and the Integration of Mitochondrial and Cytosolic Substrate CyclesATP-independent glucose stimulation of sphingosine kinase in rat pancreatic islets.Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase.Synergistic potent insulin release by combinations of weak secretagogues in pancreatic islets and INS-1 cells.Cell type-specific activation of metabolism reveals that beta-cell secretion suppresses glucagon release from alpha-cells in rat pancreatic islets.Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells.Inhibition of mitochondrial gene transcription suppresses neurotensin secretion in the human carcinoid cell line BON.Mitochondrial functional state in clonal pancreatic beta-cells exposed to free fatty acids.Inhibition of SH2-domain containing inositol phosphatase 2 (SHIP2) in insulin producing INS1E cells improves insulin signal transduction and induces proliferation.Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria.Positive Feedback Amplifies the Response of Mitochondrial Membrane Potential to Glucose Concentration in Clonal Pancreatic Beta Cells.Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells.Sex- and Dose-Specific Effects of Maternal Bisphenol A Exposure on Pancreatic Islets of First- and Second-Generation Adult Mice Offspring.
P2860
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P2860
Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Mitochondrial metabolism sets ...... ey of four fuel secretagogues.
@en
type
label
Mitochondrial metabolism sets ...... ey of four fuel secretagogues.
@en
prefLabel
Mitochondrial metabolism sets ...... ey of four fuel secretagogues.
@en
P2093
P2860
P356
P1476
Mitochondrial metabolism sets ...... ey of four fuel secretagogues.
@en
P2093
Christopher B Newgard
Claes B Wollheim
Hisamitsu Ishihara
Peter A Antinozzi
P2860
P304
11746-11755
P356
10.1074/JBC.M108462200
P407
P577
2002-01-30T00:00:00Z