Conformational change coupling the dimerization and activation of KSHV protease.
about
Current and potential treatments for ubiquitous but neglected herpesvirus infectionsSubstrate Modulation of Enzyme Activity in the Herpesvirus Protease FamilyEnzyme Inhibition by Allosteric Capture of an Inactive ConformationBroad-Spectrum Allosteric Inhibition of Herpesvirus ProteasesProbing the role of highly conserved residues in triosephosphate isomerase--analysis of site specific mutants at positions 64 and 75 in the Plasmodial enzymeInhibition of a viral enzyme by a small-molecule dimer disruptor.Allosteric regulation of protease activity by small molecules.A screening strategy for trapping the inactive conformer of a dimeric enzyme with a small molecule inhibitor.Enzymatic activities of human cytomegalovirus maturational protease assemblin and its precursor (pPR, pUL80a) are comparable: [corrected] maximal activity of pPR requires self-interaction through its scaffolding domain.Small capsid protein pORF65 is essential for assembly of Kaposi's sarcoma-associated herpesvirus capsids.Chemical rescue of I-site cleavage in living cells and in vitro discriminates between the cytomegalovirus protease, assemblin, and its precursor, pUL80a.Herpesvirus protease inhibition by dimer disruption.Novel yeast cell-based assay to screen for inhibitors of human cytomegalovirus protease in a high-throughput format.Kinetics, inhibition and oligomerization of Epstein-Barr virus protease.Induced structure of a helical switch as a mechanism to regulate enzymatic activity.Phosphorylation of human small heat shock protein HspB8 (Hsp22) by ERK1 protein kinase.
P2860
Q27023452-77D23D62-DFB9-4789-859A-D6C43BD9A3A3Q27648190-55F2B7A2-53C6-4E60-85A2-35468F75CAF4Q27670647-1001A1AD-0416-4D03-A2D5-C2D074C25D1AQ27684483-D251FA7D-9A4B-439F-B23E-3691268F1E0DQ27701621-3B6F2008-9BF4-4618-9DAF-7C664142C454Q33487129-14F9D8FB-4318-4DA9-A872-7EB6D2A5DAE2Q33601580-E3867F09-57CE-4A51-A94D-BF8650456780Q34407579-5A5B730B-0DCE-4320-BF9D-8612628056FEQ35785306-4363F544-9D6F-4C2D-9B3B-DF1FEB2886CFQ39763650-155B47E1-DCEF-4123-AB31-76778D54E136Q40394801-C49A1562-001B-4FF2-BD26-52D1D5BC8050Q40887106-6929BE2F-014C-4F4D-B100-F130C32683F2Q43105250-81B7849D-E49B-4F97-8BFC-91CD70145E4DQ45409905-C9CD68B7-8F39-495F-9DAD-82808BCEA695Q46157796-E716F2D8-B0D9-470B-A59C-9ABB71BE7B4DQ54593816-A47D8692-A0CE-4E97-A4F8-6EF95B7252FC
P2860
Conformational change coupling the dimerization and activation of KSHV protease.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Conformational change coupling the dimerization and activation of KSHV protease.
@en
type
label
Conformational change coupling the dimerization and activation of KSHV protease.
@en
prefLabel
Conformational change coupling the dimerization and activation of KSHV protease.
@en
P2093
P356
P1433
P1476
Conformational change coupling the dimerization and activation of KSHV protease.
@en
P2093
Berj G Demirjian
Charles S Craik
K Kinkead Reiling
Todd R Pray
P304
P356
10.1021/BI011753G
P407
P577
2002-02-01T00:00:00Z