Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists.
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Enhanced spontaneous activity of the mu opioid receptor by cysteine mutations: characterization of a tool for inverse agonist screeningDiscovery and cardioprotective effects of the first non-Peptide agonists of the G protein-coupled prokineticin receptor-1Visualization of a functionally enhanced GFP-tagged galanin R2 receptor in PC12 cells: constitutive and ligand-induced internalizationThe effect of angiotensin II on intracellular pH is mediated by AT(1) receptor translocation.An angiotensin II type 1 receptor activation switch patch revealed through evolutionary trace analysis.Repeated administration of angiotensin II reduces its dipsogenic effect without affecting saline intakeMelanocortin-1 receptor structure and functional regulation.Renal proximal tubule angiotensin AT1A receptors regulate blood pressureGain-of-function mutant of angiotensin II receptor, type 1A, causes hypertension and cardiovascular fibrosis in mice.Mutations of CB1 T210 produce active and inactive receptor forms: correlations with ligand affinity, receptor stability, and cellular localization.Agonist-independent interactions between beta-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis.Constitutive Desensitization of Opioid Receptors in Peripheral Sensory Neurons.GPR18 undergoes a high degree of constitutive trafficking but is unresponsive to N-Arachidonoyl Glycine.Neutral antagonist activity of naltrexone and 6beta-naltrexol in naïve and opioid-dependent C6 cells expressing a mu-opioid receptor.Cleavage of the angiotensin II type 1 receptor and nuclear accumulation of the cytoplasmic carboxy-terminal fragment.Characterization of the residues in helix 8 of the human beta1-adrenergic receptor that are involved in coupling the receptor to G proteins.The AT1A receptor "gain-of-function" mutant N111S/delta329 is both constitutively active and hyperreactive to angiotensin II.Role of tyrosine phosphorylation in the regulation of cleavage secretion of angiotensin-converting enzyme.Agonist-independent internalization of metabotropic glutamate receptor 1a is arrestin- and clathrin-dependent and is suppressed by receptor inverse agonists.Galphaq-coupled receptor internalization specifically induced by Galphaq signaling. Regulation by EBP50.Regulated and constitutive activation of specific signalling pathways by the human S1P5 receptor.Lysophosphatidylcholine-induced surface redistribution regulates signaling of the murine G protein-coupled receptor G2A.Role of the second disulfide bridge (Cys(18)-Cys(274)) in stabilizing the inactive AT₁ receptor.The carboxyl terminus of human cytomegalovirus-encoded 7 transmembrane receptor US28 camouflages agonism by mediating constitutive endocytosis."Network leaning" as a mechanism of insurmountable antagonism of the angiotensin II type 1 receptor by non-peptide antagonists.Axonal targeting of the 5-HT1B serotonin receptor relies on structure-specific constitutive activation.
P2860
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P2860
Constitutive internalization of constitutively active agiotensin II AT(1A) receptor mutants is blocked by inverse agonists.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Constitutive internalization o ...... s blocked by inverse agonists.
@en
type
label
Constitutive internalization o ...... s blocked by inverse agonists.
@en
prefLabel
Constitutive internalization o ...... s blocked by inverse agonists.
@en
P2093
P2860
P356
P1476
Constitutive internalization o ...... s blocked by inverse agonists.
@en
P2093
Charles Parnot
Eric Clauser
Sabine Bardin
P2860
P304
P356
10.1074/JBC.M108398200
P407
P577
2001-11-29T00:00:00Z