Partial activation of antithrombin without heparin through deletion of a unique sequence on the reactive site loop of the serpin.
about
Antithrombin-S195A factor Xa-heparin structure reveals the allosteric mechanism of antithrombin activationInhibitory properties of the P1 Tyr variant of antithrombin.Role of the residues of the 39-loop in determining the substrate and inhibitor specificity of factor IXa.Characterization of a heparin-binding site on the catalytic domain of factor XIa: mechanism of heparin acceleration of factor XIa inhibition by the serpins antithrombin and C1-inhibitorMolecular determinants of the mechanism underlying acceleration of the interaction between antithrombin and factor Xa by heparin pentasaccharide.Characterization of Protein Z-Dependent Protease Inhibitor/Antithrombin Chimeras Provides Insight into the Serpin Specificity of Coagulation Proteases.Deletion of P1 arginine in a novel antithrombin variant (antithrombin London) abolishes inhibitory activity but enhances heparin affinity and is associated with early onset thrombosis.Thrombomodulin enhances the reactivity of thrombin with protein C inhibitor by providing both a binding site for the serpin and allosterically modulating the activity of thrombin.
P2860
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P2860
Partial activation of antithrombin without heparin through deletion of a unique sequence on the reactive site loop of the serpin.
description
2001 nî lūn-bûn
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2001年の論文
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2001年学术文章
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2001年学术文章
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2001年学术文章
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2001年学术文章
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name
Partial activation of antithro ...... ctive site loop of the serpin.
@en
type
label
Partial activation of antithro ...... ctive site loop of the serpin.
@en
prefLabel
Partial activation of antithro ...... ctive site loop of the serpin.
@en
P2860
P356
P1476
Partial activation of antithro ...... ctive site loop of the serpin.
@en
P2093
Alireza R Rezaie
P2860
P304
P356
10.1074/JBC.M108544200
P407
P577
2001-11-13T00:00:00Z