Phage R4 integrase mediates site-specific integration in human cells.
about
Phage integrases for the construction and manipulation of transgenic mammalsIterative in vivo assembly of large and complex transgenes by combining the activities of phiC31 integrase and Cre recombinase.Rearranging the centromere of the human Y chromosome with phiC31 integraseGene stacking by recombinasesThe therapeutic potential of ΦC31 integrase as a gene therapy systemHybrid lentivirus-phiC31-int-NLS vector allows site-specific recombination in murine and human cells but induces DNA damage.A method for producing transgenic cells using a multi-integrase system on a human artificial chromosome vectorComplete and persistent phenotypic correction of phenylketonuria in mice by site-specific genome integration of murine phenylalanine hydroxylase cDNA.Enhancement of plasmid-mediated gene therapy for muscular dystrophy by directed plasmid integration.Serine integrase chimeras with activity in E. coli and HeLa cells.A platform for rapid prototyping of synthetic gene networks in mammalian cellsConstruction of transgenic Drosophila by using the site-specific integrase from phage phiC31Genetic therapies for cystic fibrosis lung diseaseAccuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genomeSuccessive and targeted DNA integrations in the Drosophila genome by Bxb1 and phiC31 integrases.Comparison and optimization of ten phage encoded serine integrases for genome engineering in Saccharomyces cerevisiae.Applications of the site-specific recombinase Cre to the study of genomic imprintingMultiple expression cassette exchange via TP901-1, R4, and Bxb1 integrase systems on a mouse artificial chromosomeRecombinase technology: applications and possibilitiesStreptomyces temperate bacteriophage integration systems for stable genetic engineering of actinomycetes (and other organisms).Genome engineering in actinomycetes using site-specific recombinases.Large serine recombinase domain structure and attachment site binding.New applications for phage integrases.Exogenous enzymes upgrade transgenesis and genetic engineering of farm animals.Engineering microbial hosts for production of bacterial natural productsUse of the site-specific retargeting jump-in platform cell line to support biologic drug discovery.Phage TP901-1 site-specific integrase functions in human cellsGeneration of site-specific retargeting platform cell lines for drug discovery using phiC31 and R4 integrases.Synapsis and DNA cleavage in phiC31 integrase-mediated site-specific recombination.Actinophage R4 integrase-based site-specific chromosomal integration of non-replicative closed circular DNA.The conjugative transposon Tn5397 has a strong preference for integration into its Clostridium difficile target site.Site-specific recombinase strategy to create induced pluripotent stem cells efficiently with plasmid DNA.Construction of a stepwise gene integration system by transient expression of actinophage R4 integrase in cyanobacterium Synechocystis sp. PCC 6803.Logic Synthesis of Recombinase-Based Genetic Circuits.Evaluation of an Hprt-Luciferase Reporter Gene on a Mammalian Artificial Chromosome in Response to Cytotoxicity.Genome analysis of the staphylococcal temperate phage DW2 and functional studies on the endolysin and tail hydrolase.TG1 integrase-based system for site-specific gene integration into bacterial genomes.Evaluating the efficiency of phiC31 integrase-mediated monoclonal antibody expression in CHO cells.Synthetic recombinase-based state machines in living cells.Ectopic Expression of O Antigen in Bordetella pertussis by a Novel Genomic Integration System.
P2860
Q24798494-B23A1A74-AB73-4A95-9982-B86944FA6EC4Q24813037-1F28B359-D510-47F1-B51A-649046878636Q24816271-21E9D98F-4FB0-46AA-94EA-D942DE67E59FQ26786485-EA45CAC5-5EE3-4287-B434-44C02A1FBF72Q28242655-E0973AC7-5A6F-4627-B9BF-B2EFEA29CDCAQ33794201-E0751970-C48D-4DEC-B192-7AE1BE984D36Q33842218-2750EE1D-33D4-4515-B93E-96AD10F2E29CQ34098361-B6E6E578-21E9-4E22-8801-F729128413A5Q34249636-4FF2B501-840D-47D0-AD89-43E4F954AAA8Q34340973-33BE1DC5-734B-4B77-9ABE-2164822AFC55Q34579727-B277D368-1984-4BCB-B072-8DD1A7F9DE28Q34644225-B8F7404C-EFAF-4CF8-943A-1BA31815C93AQ34982862-45A26F62-DCEB-40C8-983B-146EF65E1C8AQ35020836-8133A36D-E455-4751-B145-303597E352BFQ35221577-44B98A7A-C075-4C04-A6D5-52B771178FA9Q35918607-15CAA402-5F9B-4F02-A2E0-DB953D359769Q37274362-FBD6D368-B7BD-40E1-BCDF-DAB88FD93AE3Q37681644-1CB2BDD8-310A-4474-A9CA-3249A15DA13BQ37802791-31CE68D0-16A7-4042-B133-C51F5D474369Q37967385-F339B017-3D2E-4868-9A6B-89C12C91E2D1Q38098862-750BF92B-1804-4A09-9E9E-4ED51577E4A2Q38131813-A0A7B457-746B-44C1-AF88-0DFFFE2D16B9Q38214395-E9F87CE3-66D1-4091-BC90-E4146DEF507CQ38337835-A9E751EE-1CFB-41A7-85A8-300C1BDC9FE0Q38806940-8E583DBF-45C5-4F78-A2F0-415FA554D9CFQ38926027-D1FA6412-AD53-483B-9089-69B5BFE455DDQ39679557-6E004304-990E-4AD1-99E4-CCC9970C26A3Q39788824-1F9433FB-98DC-4492-A9F6-D5A1B4B911ABQ40899785-520A8302-EE63-4517-A0B9-52E9CA456CA7Q40913881-B115B589-9EEA-4BE7-B861-0673C23BFB6CQ41668794-C1D8ABBE-87F4-49ED-9440-CFCAA0E5908EQ41831020-AF88FC16-FD97-46C7-9D71-2AF7C1916F9EQ42230810-20C80596-8710-4F1F-970C-EEAA8D88571BQ42373949-237EC874-FB77-48FC-8C3E-B84282B364E8Q42381661-84CAB015-5EFD-4031-AA19-FDADFB002468Q42773690-73774A9D-3988-49E7-9477-74339C002EADQ43587970-C6FCE27F-6BFD-46BC-923D-0C2501EBF18CQ47693009-0F05B930-A981-4AAD-A66A-75DF3AE80545Q49154884-031D42F1-9797-41D5-9B66-23819607B353Q49402822-FEE44A40-1AFA-4391-B119-554CB9A145C3
P2860
Phage R4 integrase mediates site-specific integration in human cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Phage R4 integrase mediates site-specific integration in human cells.
@en
type
label
Phage R4 integrase mediates site-specific integration in human cells.
@en
prefLabel
Phage R4 integrase mediates site-specific integration in human cells.
@en
P2093
P1433
P1476
Phage R4 integrase mediates site-specific integration in human cells.
@en
P2093
P304
P356
10.1016/S0378-1119(01)00711-9
P407
P577
2001-10-01T00:00:00Z