Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
about
Opposing roles of serine/threonine kinases MEKK1 and LOK in regulating the CD28 responsive element in T-cellsCloning and characterization of ALX, an adaptor downstream of CD28Immunobiology of allogeneic peripheral blood mononuclear cells mobilized with granulocyte-colony stimulating factor.Negative transcriptional regulation in anergic T cells.B7-1 mediated costimulation regulates pancreatic autoimmunity.Antigen-unspecific B cells and lymphoid dendritic cells both show extensive surface expression of processed antigen-major histocompatibility complex class II complexes after soluble protein exposure in vivo or in vitro.In vivo stimulation of I kappa B phosphorylation is not sufficient to activate NF-kappa BRegulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: both nuclear and cytoplasmic RNAs are regulated with complex kinetics.Biphasic regulation of Il2 transcription in CD4+ T cells: roles for TNF-alpha receptor signaling and chromatin structure.Transmembrane TNF-TNFR2 Impairs Th17 Differentiation by Promoting Il2 Expression.IL-15 functions as a danger signal to regulate tissue-resident T cells and tissue destructionIn vivo anergized CD4+ T cells express perturbed AP-1 and NF-kappa B transcription factors.Analysis of proteins that interact with the IL-2 regulatory region in patients with rheumatic diseases.Negative regulation of interleukin-2 and p38 mitogen-activated protein kinase during T-cell activation by the adaptor ALX.Innate Control of Adaptive Immunity: Beyond the Three-Signal Paradigm.Costimulation by B7-1 and LFA-3 targets distinct nuclear factors that bind to the interleukin-2 promoter: B7-1 negatively regulates LFA-3-induced NF-AT DNA binding.CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites.Envelope glycoproteins of human immunodeficiency virus type 1: profound influences on immune functions.The ALX Src homology 2 domain is both necessary and sufficient to inhibit T cell receptor/CD28-mediated up-regulation of RE/AP.Costimulation requirement for AP-1 and NF-kappa B transcription factor activation in T cells.Anergic T cells are defective in both jun NH2-terminal kinase and mitogen-activated protein kinase signaling pathways.c-rel regulation of IL-2 gene expression may be mediated through activation of AP-1.Interleukin-2 and systemic lupus erythematosus--fifteen years later.
P2860
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P2860
Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
@en
type
label
Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
@en
prefLabel
Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
@en
P2093
P2860
P1476
Molecular regulation of the IL-2 gene: rheostatic control of the immune system.
@en
P2093
P2860
P304
P356
10.1111/J.1600-065X.1993.TB01516.X
P577
1993-06-01T00:00:00Z