Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
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Opportunities for functional selectivity in GPCR antibodiesStructure-Based Design, Synthesis, and Characterization of Dual Hotspot Small-Molecule HIV-1 Entry InhibitorsHigh-level production, solubilization and purification of synthetic human GPCR chemokine receptors CCR5, CCR3, CXCR4 and CX3CR1Molecular dynamics simulations on SDF-1alpha: binding with CXCR4 receptorPhysiological levels of virion-associated human immunodeficiency virus type 1 envelope induce coreceptor-dependent calcium flux.Selection of phage-displayed peptides on live adherent cells in microfluidic channels.Identification of CD4 and transferrin receptor antibodies by CXCR4 antibody-guided Pathfinder selection.The use of phage display in the study of receptors and their ligands.Soluble CD4 and CD4-mimetic compounds inhibit HIV-1 infection by induction of a short-lived activated state.HIV-1 clade B Tat, but not clade C Tat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells.Thermal stability of the human immunodeficiency virus type 1 (HIV-1) receptors, CD4 and CXCR4, reconstituted in proteoliposomes.A V3 loop-dependent gp120 element disrupted by CD4 binding stabilizes the human immunodeficiency virus envelope glycoprotein trimer.Single-molecule analysis of human immunodeficiency virus type 1 gp120-receptor interactions in living cells.Solid-phase proteoliposomes containing human immunodeficiency virus envelope glycoproteins.Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope.Identification of conserved and variable structures in the human immunodeficiency virus gp120 glycoprotein of importance for CXCR4 bindingSensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kineticsIdentification of gp120 binding sites on CXCR4 by using CD4-independent human immunodeficiency virus type 2 Env proteins.Novel compounds containing multiple guanide groups that bind the HIV coreceptor CXCR4.Design, synthesis and biological evaluation of small molecule inhibitors of CD4-gp120 binding based on virtual screeningThe isolation of novel phage display-derived human recombinant antibodies against CCR5, the major co-receptor of HIVMacrophage-sensory neuronal interaction in HIV-1 gp120-induced neurotoxicity‡.Phage display and hybridoma generation of antibodies to human CXCR2 yields antibodies with distinct mechanisms and epitopes.Functional Mimetics of the HIV-1 CCR5 Co-Receptor Displayed on the Surface of Magnetic Liposomes.Replication-competent variants of human immunodeficiency virus type 2 lacking the V3 loop exhibit resistance to chemokine receptor antagonists.HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cellsCCL2 increases X4-tropic HIV-1 entry into resting CD4+ T cells.Small-molecule CD4 mimics interact with a highly conserved pocket on HIV-1 gp120.Expression, surface immobilization, and characterization of functional recombinant cannabinoid receptor CB2Factors that increase the effective concentration of CXCR4 dictate feline immunodeficiency virus tropism and kinetics of replication.Maturation of the Gag core decreases the stability of retroviral lipid membranes.Replacement of the V3 domain in the surface subunit of the feline immunodeficiency virus envelope glycoprotein with the equivalent region of a T cell-tropic human immunodeficiency virus type 1 results in a chimeric surface protein that efficiently bCD4-induced T-20 binding to human immunodeficiency virus type 1 gp120 blocks interaction with the CXCR4 coreceptorEscaping the flatlands: new approaches for studying the dynamic assembly and activation of GPCR signaling complexes.Heparan sulfate differentially controls CXCL12α- and CXCL12γ-mediated cell migration through differential presentation to their receptor CXCR4.Overproduction of human M₃ muscarinic acetylcholine receptor: an approach toward structural studies.The synthesis and high-level expression of a beta2-adrenergic receptor gene in a tetracycline-inducible stable mammalian cell line.Impact of mutations in the coreceptor binding site on human immunodeficiency virus type 1 fusion, infection, and entry inhibitor sensitivity.Purification and biochemical characterization of the D6 chemokine receptorAssembly of G protein-coupled receptors onto nanosized bacterial magnetic particles using Mms16 as an anchor molecule.
P2860
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P2860
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
@en
type
label
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
@en
prefLabel
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
@en
P2093
P2860
P356
P1476
Ligand binding characteristics of CXCR4 incorporated into paramagnetic proteoliposomes.
@en
P2093
Babcock GJ
Mirzabekov T
Wojtowicz W
P2860
P304
38433-38440
P356
10.1074/JBC.M106229200
P407
P577
2001-08-06T00:00:00Z