Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide.
about
Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratioAutosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor proteinAssociation of a novel human FE65-like protein with the cytoplasmic domain of the beta-amyloid precursor proteinLysosomal processing of amyloid precursor protein to A beta peptides: a distinct role for cathepsin SA metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor.Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domainsHuman serum albumin inhibits Abeta fibrillization through a "monomer-competitor" mechanismThe neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer diseaseCaenorhabditis elegans as a model organism to study APP functionCerebrospinal fluid and blood biomarkers in Alzheimer's diseaseAmyloid-Beta Induced Changes in Vesicular Transport of BDNF in Hippocampal NeuronsMolecular Structure of Aggregated Amyloid-β: Insights from Solid-State Nuclear Magnetic ResonanceInflammation, antichymotrypsin, and lipid metabolism: autogenic etiology of Alzheimer's diseaseConstitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloproteaseEvidence-Based Research in Complementary and Alternative Medicine III: Treatment of Patients with Alzheimer's DiseaseTrafficking and proteolytic processing of APPNeuroprotective and neurorescuing effects of isoform-specific nitric oxide synthase inhibitors, nitric oxide scavenger, and antioxidant against beta-amyloid toxicityPresenilin-dependent gamma-secretase processing of beta-amyloid precursor protein at a site corresponding to the S3 cleavage of NotchStructural Analysis and Aggregation Propensity of Pyroglutamate Aβ(3-40) in Aqueous TrifluoroethanolHuntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neuronsBMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease modelsExpanded high-resolution genetic study of 109 Swedish families with Alzheimer's diseaseQuantification of Alzheimer pathology in ageing and dementia: age-related accumulation of amyloid-beta(42) peptide in vascular dementia.An in vivo assay for the identification of target proteases which cleave membrane-associated substrates.CSF biomarkers for mild cognitive impairment.Highly conserved and disease-specific patterns of carboxyterminally truncated Abeta peptides 1-37/38/39 in addition to 1-40/42 in Alzheimer's disease and in patients with chronic neuroinflammation.Biphasic modulation of protein kinase C and enhanced cell toxicity by amyloid beta peptide and anoxia in neuronal cultures.Involvement of cell cycle elements, cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death.CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementiaJun NH2-terminal kinase (JNK) interacting protein 1 (JIP1) binds the cytoplasmic domain of the Alzheimer's beta-amyloid precursor protein (APP).Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases.Palmitate Increases β-site AβPP-Cleavage Enzyme 1 Activity and Amyloid-β Genesis by Evoking Endoplasmic Reticulum Stress and Subsequent C/EBP Homologous Protein Activation.Biomarkers in translational research of Alzheimer's diseaseN-Terminal Extensions Retard Aβ42 Fibril Formation but Allow Cross-Seeding and Coaggregation with Aβ42The use of cleavage site specific antibodies to delineate protein processing and breakdown pathways.The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.Management of neurological disorders: dementia.Changes in reflectin protein phosphorylation are associated with dynamic iridescence in squid.The beta-amyloid precursor protein and its derivatives: from biology to learning and memory processes.The secretases: enzymes with therapeutic potential in Alzheimer disease.
P2860
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P2860
Cellular processing of beta-amyloid precursor protein and the genesis of amyloid beta-peptide.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Cellular processing of beta-am ...... nesis of amyloid beta-peptide.
@en
type
label
Cellular processing of beta-am ...... nesis of amyloid beta-peptide.
@en
prefLabel
Cellular processing of beta-am ...... nesis of amyloid beta-peptide.
@en
P1433
P1476
Cellular processing of beta-am ...... nesis of amyloid beta-peptide.
@en
P2093
P304
P356
10.1016/0092-8674(93)90312-E
P407
P577
1993-12-01T00:00:00Z