A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.
about
Kinase-independent mechanisms of resistance of leukemia stem cells to tyrosine kinase inhibitorsA novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesisMutant forms of growth factor-binding protein-2 reverse BCR-ABL-induced transformation.The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation.The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.FoxO tumor suppressors and BCR-ABL-induced leukemia: a matter of evasion of apoptosis.Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl.Structural and signaling requirements for BCR-ABL-mediated transformation and inhibition of apoptosis.BCR-ABL and v-SRC tyrosine kinase oncoproteins support normal erythroid development in erythropoietin receptor-deficient progenitor cells.Increased sensitivity to apoptotic stimuli in c-abl-deficient progenitor B-cell linesRegulated expression of P210 Bcr-Abl during embryonic stem cell differentiation stimulates multipotential progenitor expansion and myeloid cell fateThe insulin-like growth factor system as a potential therapeutic target in gastrointestinal stromal tumors.The Hepatocyte Growth Factor (HGF)/Met Axis: A Neglected Target in the Treatment of Chronic Myeloproliferative Neoplasms?BCR/ABL induces multiple abnormalities of cytoskeletal function.Inhibition of the Raf-1 kinase by cyclic AMP agonists causes apoptosis of v-abl-transformed cellsRoles of Bim in apoptosis of normal and Bcr-Abl-expressing hematopoietic progenitors.
P2860
Q26849792-203703D5-96D9-4CE3-9745-DF7973AEB20BQ28609040-4704F797-E5B7-45A0-8E34-2BA4D1AAEE62Q30175784-DDC55FB7-196E-4B2B-9EB7-65F37C398A25Q30192925-8E020E17-C366-489A-AD80-B9C07CF89D66Q33720267-0C7C493D-CD55-451A-8BC2-6FDA50B044F7Q33961839-C6E67A81-F3D0-4366-8B46-6F548D7EF17CQ36334327-48FCDB8A-E0A8-4F78-9BFD-6D40540A2393Q36365946-1484FE05-BCF3-483E-B039-E47FF815FEA5Q36555271-1F3FD27C-45DA-4BBA-A93C-3E0C75087A1BQ36668207-17AE21C0-32EC-4A8D-B878-4C3952CBDA36Q36688513-E3061494-C3DC-4650-87AA-587312CB5EE3Q37115618-91258416-7468-410C-A299-960BDBDFE2B4Q37279733-91B76E04-0D74-4475-B6A9-F0CCCFA71990Q38239580-C5F85437-9427-4ED1-B187-41CECB249EC1Q39786673-A730947C-E840-4681-BDBC-CF105FEFFB86Q40022357-3300839A-1393-4616-8E5B-44F57B0EEC49Q40540288-049B272A-85CC-4137-9931-EC6DE9143CE2
P2860
A temperature sensitive p210 BCR-ABL mutant defines the primary consequences of BCR-ABL tyrosine kinase expression in growth factor dependent cells.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
1994年學術文章
@zh
1994年學術文章
@zh-hant
name
A temperature sensitive p210 B ...... growth factor dependent cells.
@en
type
label
A temperature sensitive p210 B ...... growth factor dependent cells.
@en
prefLabel
A temperature sensitive p210 B ...... growth factor dependent cells.
@en
P2093
P2860
P1433
P1476
A temperature sensitive p210 B ...... growth factor dependent cells
@en
P2093
Kabarowski JH
Wiedemann LM
P2860
P304
P356
10.1002/J.1460-2075.1994.TB06934.X
P407
P577
1994-12-01T00:00:00Z