Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog.
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Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analoguesMultidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseasesPulmonary metabolism of resveratrol: in vitro and in vivo evidenceATP-binding cassette (ABC) transporters in normal and pathological lungUrinary biomarkers of smokers' exposure to tobacco smoke constituents in tobacco products assessment: a fit for purpose approachRole of the NH2-terminal membrane spanning domain of multidrug resistance protein 1/ABCC1 in protein processing and traffickingTobacco carcinogen NNK transporter MRP2 regulates CFTR function in lung epithelia: implications for lung cancerRole of glutathione in the regulation of Cisplatin resistance in cancer chemotherapy.Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance.Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma.The MRP family of drug efflux pumps.Loss of multidrug resistance-associated protein 1 potentiates chronic doxorubicin-induced cardiac dysfunction in mice.UPLC-MS/MS method for the determination of tobacco-specific biomarker NNAL, tamoxifen and its main metabolites in rat plasma.On the putative co-transport of drugs by multidrug resistance proteins.Substrate recognition and transport by multidrug resistance protein 1 (ABCC1).Insight in eukaryotic ABC transporter function by mutation analysis.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunitiesLoss of Mrp1 Potentiates Doxorubicin-Induced Cytotoxicity in Neonatal Mouse Cardiomyocytes and Cardiac FibroblastsPlasma membrane glutathione transporters and their roles in cell physiology and pathophysiologyThe role of diet on the clinical pharmacology of oral antineoplastic agents.Environmental chemicals as substrates, inhibitors or inducers of drug transporters: implication for toxicokinetics, toxicity and pharmacokinetics.Renal transport of organic anions and cations.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Placental ABC Transporters: Biological Impact and Pharmaceutical Significance.Selenium-dependent and -independent transport of arsenic by the human multidrug resistance protein 2 (MRP2/ABCC2): implications for the mutual detoxification of arsenic and selenium.Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.Role of GSH in estrone sulfate binding and translocation by the multidrug resistance protein 1 (MRP1/ABCC1).Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.Mutational analysis of ionizable residues proximal to the cytoplasmic interface of membrane spanning domain 3 of the multidrug resistance protein, MRP1 (ABCC1): glutamate 1204 is important for both the expression and catalytic activity of the transpArsenic transport by the human multidrug resistance protein 1 (MRP1/ABCC1). Evidence that a tri-glutathione conjugate is required.Identification of proline residues in the core cytoplasmic and transmembrane regions of multidrug resistance protein 1 (MRP1/ABCC1) important for transport function, substrate specificity, and nucleotide interactions.Functional importance of polar and charged amino acid residues in transmembrane helix 14 of multidrug resistance protein 1 (MRP1/ABCC1): identification of an aspartate residue critical for conversion from a high to low affinity substrate binding staLocalization of the GSH-dependent photolabelling site of an agosterol A analog on human MRP1.Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).Multiple membrane-associated tryptophan residues contribute to the transport activity and substrate specificity of the human multidrug resistance protein, MRP1.Photolabeling of human and murine multidrug resistance protein 1 with the high affinity inhibitor [125I]LY475776 and azidophenacyl-[35S]glutathione.
P2860
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P2860
Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Transport of the beta -O-glucu ...... non-sulfur-containing analog.
@en
type
label
Transport of the beta -O-glucu ...... non-sulfur-containing analog.
@en
prefLabel
Transport of the beta -O-glucu ...... non-sulfur-containing analog.
@en
P2093
P356
P1476
Transport of the beta -O-glucu ...... non-sulfur-containing analog.
@en
P2093
P304
27846-27854
P356
10.1074/JBC.M102453200
P407
P577
2001-05-25T00:00:00Z