Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model.
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Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes.Activin B can signal through both ALK4 and ALK7 in gonadotrope cellsA proteomic comparison of immature and mature mouse gonadotrophs reveals novel differentially expressed nuclear proteins that regulate gonadotropin gene transcription and RNA splicingActivin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1Nuclear factor Y and steroidogenic factor 1 physically and functionally interact to contribute to cell-specific expression of the mouse Follicle-stimulating hormone-beta geneHomeodomain Proteins SIX3 and SIX6 Regulate Gonadotrope-specific Genes During Pituitary Development.Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects.Heterozygous deletion of ventral anterior homeobox (vax1) causes subfertility in miceCREB binding protein (CBP) activation is required for luteinizing hormone beta expression and normal fertility in miceImpaired FSHbeta expression in the pituitaries of Foxl2 mutant animals.Gonadotropin-releasing hormone pulse sensitivity of follicle-stimulating hormone-beta gene is mediated by differential expression of positive regulatory activator protein 1 factors and corepressors SKIL and TGIF1.Leptin increases L-type Ca2+ channel expression and GnRH-stimulated LH release in LbetaT2 gonadotropesGonadotrope-specific expression and regulation of ovine follicle stimulating hormone Beta: transgenic and adenoviral approaches using primary murine gonadotropes.Activator protein-1 and smad proteins synergistically regulate human follicle-stimulating hormone beta-promoter activityHormones in synergy: regulation of the pituitary gonadotropin genes.Minireview: Activin Signaling in Gonadotropes: What Does the FOX say… to the SMAD?GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene.FoxL2 Is required for activin induction of the mouse and human follicle-stimulating hormone beta-subunit genes.Runt-related transcription factors impair activin induction of the follicle-stimulating hormone {beta}-subunit gene.Generation of immortal cell lines from the adult pituitary: role of cAMP on differentiation of SOX2-expressing progenitor cells to mature gonadotropes.Transcriptional activation of the ovine follicle-stimulating hormone-beta gene by gonadotropin-releasing hormone involves multiple signal transduction pathways.A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone.An Otx-related homeodomain protein binds an LHbeta promoter element important for activation during gonadotrope maturation.Phylogenetic footprinting reveals evolutionarily conserved regions of the gonadotropin-releasing hormone gene that enhance cell-specific expression.Androgen regulates follicle-stimulating hormone beta gene expression in an activin-dependent manner in immortalized gonadotropes.Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell lineDevelopmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families.Activin regulates luteinizing hormone beta-subunit gene expression through Smad-binding and homeobox elements.p38 mitogen-activated protein kinase is critical for synergistic induction of the FSH(beta) gene by gonadotropin-releasing hormone and activin through augmentation of c-Fos induction and Smad phosphorylationDifferent signaling pathways control acute induction versus long-term repression of LHbeta transcription by GnRHPulse sensitivity of the luteinizing hormone beta promoter is determined by a negative feedback loop Involving early growth response-1 and Ngfi-A binding protein 1 and 2.A FoxL in the Smad house: activin regulation of FSH.Research resource: Gonadotropin-releasing hormone receptor-mediated signaling network in LbetaT2 cells: a pathway-based web-accessible knowledgebase.Androgens, progestins, and glucocorticoids induce follicle-stimulating hormone beta-subunit gene expression at the level of the gonadotropeDirect binding of AP-1 (Fos/Jun) proteins to a SMAD binding element facilitates both gonadotropin-releasing hormone (GnRH)- and activin-mediated transcriptional activation of the mouse GnRH receptor gene.Ubiquitin C-terminal hydrolase l1 is expressed in mouse pituitary gonadotropes in vivo and gonadotrope cell lines in vitro.Inhibin at 90: from discovery to clinical application, a historical reviewConstitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropesMicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIACharacterization of a MAPK scaffolding protein logic gate in gonadotropes.
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P2860
Cell-specific transcriptional regulation of follicle-stimulating hormone-beta by activin and gonadotropin-releasing hormone in the LbetaT2 pituitary gonadotrope cell model.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Cell-specific transcriptional ...... uitary gonadotrope cell model.
@en
type
label
Cell-specific transcriptional ...... uitary gonadotrope cell model.
@en
prefLabel
Cell-specific transcriptional ...... uitary gonadotrope cell model.
@en
P2093
P356
P1433
P1476
Cell-specific transcriptional ...... uitary gonadotrope cell model.
@en
P2093
F Pernasetti
J S Bailey
P L Mellon
S B Rosenberg
V V Vasilyev
W L Miller
P304
P356
10.1210/EN.142.6.2284
P407
P577
2001-06-01T00:00:00Z