Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.
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Identification of xenoestrogens in food additives by an integrated in silico and in vitro approachEndocrinology and hormone therapy in breast cancer: selective oestrogen receptor modulators and downregulators for breast cancer - have they lost their way?The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practiceUpdate on bazedoxifene: a novel selective estrogen receptor modulatorImproved docking, screening and selectivity prediction for small molecule nuclear receptor modulators using conformational ensembles.Parallel synthesis of a desketoraloxifene analogue library via iodocyclization/palladium-catalyzed coupling.SERMs attenuate estrogen-induced malignant transformation of human mammary epithelial cells by upregulating detoxification of oxidative metabolites.Selective estrogen receptor modulators: tissue specificity and clinical utility.From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).The evolution of nonsteroidal antiestrogens to become selective estrogen receptor modulatorsBiochemical mechanisms of drug action: what does it take for success?Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader.Bazedoxifene: a new selective estrogen receptor modulator for the treatment of postmenopausal osteoporosis.Efficacy and safety of bazedoxifene for postmenopausal osteoporosis.The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1.The effects of 17β-estradiol and a selective estrogen receptor modulator, bazedoxifene, on ovarian carcinogenesis.Selective Estrogen Receptor Modulators Suppress Hif1α Protein Accumulation in Mouse Osteoclasts.Structure-based design of eugenol analogs as potential estrogen receptor antagonistsProfile of bazedoxifene/conjugated estrogens for the treatment of estrogen deficiency symptoms and osteoporosis in women at risk of fractureBazedoxifene for the prevention of postmenopausal osteoporosisPotential of selective estrogen receptor modulators as treatments and preventives of breast cancer.Bazedoxifene: a selective estrogen-receptor modulator.Pharmacokinetic evaluation of bazedoxifene for the treatment of osteoporosis.Bazedoxifene + conjugated estrogens in HT for the prevention of osteoporosis and treatment of vasomotor symptoms associated with the menopause.Tethered indoles as functionalizable ligands for the estrogen receptor.Multiple-dose, safety, pharmacokinetics, and pharmacodynamics of a new selective estrogen receptor modulator, ERA-923, in healthy postmenopausal women.Polymer-assisted solution phase synthesis of the antihyperglycemic agent Rosiglitazone (Avandia).Selective estrogen receptor modulators (SERMS).Selective Estrogen Receptor ModulatorsGeneral and Efficient Synthesis of Indoles through Triazene-Directed C-H Annulation
P2860
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P2860
Design, synthesis, and preclinical characterization of novel, highly selective indole estrogens.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Design, synthesis, and preclin ...... ly selective indole estrogens.
@en
type
label
Design, synthesis, and preclin ...... ly selective indole estrogens.
@en
prefLabel
Design, synthesis, and preclin ...... ly selective indole estrogens.
@en
P2093
P356
P1476
Design, synthesis, and preclin ...... ly selective indole estrogens.
@en
P2093
Abou-Gharbia MA
Collini MD
Greenberger LM
Henderson RA
Kharode YP
Marzolf JT
P304
P356
10.1021/JM010086M
P407
P577
2001-05-01T00:00:00Z