Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12.
about
Prime-boost vaccination with plasmid and adenovirus gene vaccines control HER2/neu+ metastatic breast cancer in mice.Interleukin 12: still a promising candidate for tumor immunotherapy?Dendritic cells transfected with Her2 antigen-encoding RNA replicons cross-prime CD8 T cells and protect mice against tumor challenge.Breast cancer vaccines: a clinical reality or fairy tale?Characterizing complex polysera produced by antigen-specific immunization through the use of affinity-selected mimotopesNew vaccine developmentCCL21 Cancer Immunotherapy.Anti-HER2 vaccines: new prospects for breast cancer therapyIL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells.Antisense therapy for restenosis following percutaneous coronary intervention.Influenza virus-like particles engineered by protein transfer with tumor-associated antigens induces protective antitumor immunity.Adenovirus as vehicle for anticancer genetic immunotherapy.Combinational adenovirus-mediated gene therapy and dendritic cell vaccine in combating well-established tumors.Vaccine immunotherapy in breast cancer treatment: promising, but still early.Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice.Enhancement of antitumor activity of gammaretrovirus carrying IL-12 gene through genetic modification of envelope targeting HER2 receptor: a promising strategy for bladder cancer therapy.Influence of whole peptidoglycan of bifidobacterium on cytotoxic effectors produced by mouse peritoneal macrophages.Route of administration influences the antitumor effects of bone marrow-derived dendritic cells engineered to produce interleukin-12 in a metastatic mouse prostate cancer model.HER-2/neu-gene engineered dendritic cell vaccine stimulates stronger HER-2/neu-specific immune responses compared to DNA vaccination.Differential immune responses mediated by adenovirus- and lentivirus-transduced DCs in a HER-2/neu overexpressing tumor model.Intratumoral administration of an adenovirus expressing a kinase dead form of ErbB-2 inhibits tumor growth.Natural killer cells play a critical role in the immune response following immunization with melanoma-antigen-engineered dendritic cells.Harnessing the immune system in the battle against breast cancer.Immunological properties and vaccine efficacy of murine dendritic cells simultaneously expressing melanoma-associated antigen and interleukin-12.Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice.
P2860
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P2860
Induction of ErbB-2/neu-specific protective and therapeutic antitumor immunity using genetically modified dendritic cells: enhanced efficacy by cotransduction of gene encoding IL-12.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Induction of ErbB-2/neu-specif ...... uction of gene encoding IL-12.
@en
type
label
Induction of ErbB-2/neu-specif ...... uction of gene encoding IL-12.
@en
prefLabel
Induction of ErbB-2/neu-specif ...... uction of gene encoding IL-12.
@en
P2093
P2860
P356
P1433
P1476
Induction of ErbB-2/neu-specif ...... uction of gene encoding IL-12.
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.GT.3301396
P577
2001-02-01T00:00:00Z
P5875
P6179
1012698660