Rac1 activity is required for the activation of hypoxia-inducible factor 1.
about
Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin.The possible mechanisms underlying the impairment of HIF-1α pathway signaling in hyperglycemia and the beneficial effects of certain therapiesHypoxia-Inducible Factors (HIFs) and Phosphorylation: Impact on Stability, Localization, and TransactivityThe immunological effect of hyaluronan in tumor angiogenesisImplications of Hypoxia in Breast Cancer Metastasis to BoneLack of bcr and abr promotes hypoxia-induced pulmonary hypertension in miceHIF-1α activation results in actin cytoskeleton reorganization and modulation of Rac-1 signaling in endothelial cellsRac1 and Cdc42 are regulators of HRasV12-transformation and angiogenic factors in human fibroblasts.Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo.Mitochondrial reactive oxygen species activation of p38 mitogen-activated protein kinase is required for hypoxia signaling.Mitigation of oxygen-induced retinopathy in α2β1 integrin-deficient mice.Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species.MAPK14/p38α-dependent modulation of glucose metabolism affects ROS levels and autophagy during starvation.Hypoxia as a biomarker for radioresistant cancer stem cells.Antitumorigenesis of antioxidants in a transgenic Rac1 model of Kaposi's sarcomaThe oxygen sensing signal cascade under the influence of reactive oxygen species.Hypoxia-inducible factor in thyroid carcinomaGlycogen synthase kinase 3 phosphorylates hypoxia-inducible factor 1alpha and mediates its destabilization in a VHL-independent manner.The Qo site of the mitochondrial complex III is required for the transduction of hypoxic signaling via reactive oxygen species production.Development of novel therapeutic strategies that target HIF-1.Hypoxia-induced IL-18 increases hypoxia-inducible factor-1alpha expression through a Rac1-dependent NF-kappaB pathway.Two-site substrate recognition model for the Keap1-Nrf2 system: a hinge and latch mechanism.Redox regulation of the hypoxia-inducible factor.Hyaluronic acid promotes angiogenesis by inducing RHAMM-TGFβ receptor interaction via CD44-PKCδ.Regulation of HIF-1α activity by overexpression of thioredoxin is independent of thioredoxin reductase statusRole of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia.NADPH oxidases as a source of oxidative stress and molecular target in ischemia/reperfusion injury.Rho GTPases in the regulation of pulmonary vascular barrier function.Rho GTPases modulate malignant transformation of tumor cells.Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite.Protein Kinase C Isoforms Differentially Regulate Hypoxia-Inducible Factor-1α Accumulation in Cancer Cells.Hypoxia and the modulation of the actin cytoskeleton - emerging interrelations.Phosphatidylinositol 3'-kinase signaling pathway is essential for Rac1-induced hypoxia-inducible factor-1(alpha) and vascular endothelial growth factor expression.Persisting mild hypothermia suppresses hypoxia-inducible factor-1alpha protein synthesis and hypoxia-inducible factor-1-mediated gene expression.Activation of hypoxia-inducible factor 1 during macrophage differentiation.The intravenous anesthetic propofol inhibits hypoxia-inducible factor 1 activity in an oxygen tension-dependent manner.Redox-sensitive regulation of the HIF pathway under non-hypoxic conditions in pulmonary artery smooth muscle cells.Hypoxic but not anoxic stabilization of HIF-1alpha requires mitochondrial reactive oxygen species.Lack of evidence for the involvement of the phosphoinositide 3-kinase/Akt pathway in the activation of hypoxia-inducible factors by low oxygen tension.Reversible inhibition of hypoxia-inducible factor 1 activation by exposure of hypoxic cells to the volatile anesthetic halothane.
P2860
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P2860
Rac1 activity is required for the activation of hypoxia-inducible factor 1.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Rac1 activity is required for the activation of hypoxia-inducible factor 1.
@en
type
label
Rac1 activity is required for the activation of hypoxia-inducible factor 1.
@en
prefLabel
Rac1 activity is required for the activation of hypoxia-inducible factor 1.
@en
P2860
P356
P1476
Rac1 activity is required for the activation of hypoxia-inducible factor 1.
@en
P2093
P2860
P304
21166-21172
P356
10.1074/JBC.M100677200
P407
P577
2001-03-30T00:00:00Z