Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

Item

http://www.wikidata.org/entity/Q40816462

Q40816462

about

Activation of oxidative stress-responsive signaling pathways in early splenotoxic response of aniline RhoA regulation of NF-kappaB activation is mediated by COX-2-dependent feedback inhibition of IKK in kidney epithelial cells Hyperosmotic stress activates p65/RelB NFkappaB in cultured cardiomyocytes with dichotomic actions on caspase activation and cell death Increased expression of the homologue of enhancer-of-split 1 protects neurons from beta amyloid neurotoxicity and hints at an alternative role for transforming growth factor beta1 as a neuroprotector A new family of synthetic diterpenes that regulates cytokine synthesis by inhibiting IkappaBalpha phosphorylation.Natural products as targeted modulators of the nuclear factor-kappaB pathway.Kaurenic acid: An in vivo experimental study of its anti-inflammatory and antipyretic effects.Inhibitory effect of inflexinol on nitric oxide generation and iNOS expression via inhibition of NF-kappaB activation.Analgesic effects of an ethanol extract of the fruits of Xylopia aethiopica (Dunal) A. Rich (Annonaceae) and the major constituent, xylopic acid in murine models.Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)Methyl angolensate from callus of Indian redwood induces cytotoxicity in human breast cancer cells.16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: potent mechanism-based inhibitors of recombinant ent-kaurene synthase from Arabidopsis thaliana.The influence of topic and systemic administration of copaiba oil on the alveolar wound healing after tooth extraction in rats Anti-allodynic and Anti-hyperalgesic effects of an ethanolic extract and xylopic acid from the fruits of Xylopia aethiopica in murine models of neuropathic pain.Induction of the inflammatory regulator A20 by gibberellic acid in airway epithelial cells.Biological activities and cytotoxicity of diterpenes from Copaifera spp. Oleoresins.Kaurene diterpene induces apoptosis in U87 human malignant glioblastoma cells by suppression of anti-apoptotic signals and activation of cysteine proteases.Labdane diterpenes protect against anoxia/reperfusion injury in cardiomyocytes: involvement of AKT activation.Critical role of the death receptor pathway in the antitumoral effects induced by hispanolone derivatives.Sesquiterpene lactone fraction from Artemisia khorassanica inhibits inducible nitric oxide synthase and cyclooxygenase-2 expression through the inactivation of NF-κB.A natural compound, methyl angolensate, induces mitochondrial pathway of apoptosis in Daudi cells.Methyl angolensate, a natural tetranortriterpenoid induces intrinsic apoptotic pathway in leukemic cells.Kaurane diterpenes protect against apoptosis and inhibition of phagocytosis in activated macrophages.Modulation of the age-related nuclear factor-kappaB (NF-kappaB) pathway by hesperetin.Copaiba oil effect on induced fecal peritonitis in rats.Andrographolide interferes with binding of nuclear factor-kappaB to DNA in HL-60-derived neutrophilic cells.Kaurane diterpene, kamebakaurin, inhibits NF-kappa B by directly targeting the DNA-binding activity of p50 and blocks the expression of antiapoptotic NF-kappa B target genes.Peroxisome proliferator-activated receptor gamma activation counters the detrimental effect of Helicobacter pylori lipopolysaccharide on gastric mucin synthesis.Protective effect of Ginkgo biloba leaves extract, EGb761, on myocardium injury in ischemia reperfusion rats via regulation of TLR-4/NF-κB signaling pathway.Hyperosmotic stress-dependent NFκB activation is regulated by reactive oxygen species and IGF-1 in cultured cardiomyocytes Phytochemicals for the treatment of inflammatory bowel diseases

P2860

Q28386957-A14B6C37-5C63-4DD0-9F92-B80DF8F3D3F3 Q28572424-A68EB8E3-4BAA-4E49-A2D4-9CC760C6885A Q28578560-28EFF779-5808-4FEC-B645-8555703CB6B1 Q30460471-7928E11B-79D2-4B3C-8285-13A6F3F269B6 Q30975970-05C8648C-434E-41BA-AB79-6908510B49C2 Q34127458-BCF4AACA-9BCA-4DD2-94A7-C22465F278FD Q34222838-183F69D0-5F4B-45D9-BB72-8343D1220363 Q35804789-5E54216E-E61A-4CE4-8498-DCD928AD6626 Q36470283-AE60E9F4-F45D-4D6D-BC82-98B80CF81782 Q36717554-FD1CBA51-B7E1-4386-8571-24254676C5EB Q36736676-6D2E58CE-F65E-4E7B-B6CA-65F0525F4AB8 Q37021395-23EF3A61-0C46-4630-8FB0-D74BBBEAD4E1 Q37480618-13EBC382-E711-44E9-A072-A50253FD6284 Q37718599-F9896775-AD07-4181-8653-38C8C523874F Q38263512-7269856A-3942-4AAC-B03F-402CC5717AF6 Q38889015-ED3ED5FA-37DA-4144-80AA-860EC8A586B4 Q39211543-E68EEAA1-BEDC-4271-9454-EF165864D283 Q39359620-75A7BE1C-1A5F-4681-8446-31722B9D5F90 Q39400787-C179B1F0-6BA2-4B1E-A285-D03283B07436 Q39727065-0D0643BE-EB80-40E4-AA30-F892A46AE458 Q39737535-ED0595C7-F64E-453A-A020-135809D30404 Q39914026-E197FAF4-3BA2-49EB-A391-F6B17769B900 Q40109780-FCCAE724-A9BA-40F8-B1B7-20E9664284FD Q40238594-B6E6AE48-0038-4627-9EAE-2A412B4D269F Q41008855-DDC6F544-1261-468E-8566-E870F304500F Q41895046-DB711EDE-D57F-41CC-85AA-AE2F9F341D50 Q43904711-60B85DE5-27ED-4C34-9AA1-7BCCD5DA4FFB Q44808694-F0204618-F3FD-444A-B58D-EED44149BA4C Q47094814-7EBF6460-71CF-4A68-AE32-C484418A54A5 Q57244730-7CE15642-D46B-46BC-B92A-4E2261130BFD Q58595158-D74A051A-0C32-40F1-BFA9-B147F865B81E

P2860

Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

Item

http://www.wikidata.org/entity/Q40816462

description

2001 nî lūn-bûn

@nan

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

2001年论文

@zh

2001年论文

@zh-cn

name

Inhibition of the nuclear fact ...... ctivation of ERK and p38 MAPK.

@en

type

Item

label

Inhibition of the nuclear fact ...... ctivation of ERK and p38 MAPK.

@en

prefLabel

Inhibition of the nuclear fact ...... ctivation of ERK and p38 MAPK.

@en

P1476

Inhibition of the nuclear fact ...... ctivation of ERK and p38 MAPK.

@en

P2093

A Castrillo

http://www.w3.org/2001/XMLSchema#string

A Villar

http://www.w3.org/2001/XMLSchema#string

B Rodriguez

http://www.w3.org/2001/XMLSchema#string

B de Las Heras

http://www.w3.org/2001/XMLSchema#string

L Bosca

http://www.w3.org/2001/XMLSchema#string

S Hortelano

http://www.w3.org/2001/XMLSchema#string

P2860

NF-kappaB-inducing kinase activates IKK-alpha by phosphorylation of Ser-176

Coordinate regulation of IkappaB kinases by mitogen-activated protein kinase kinase kinase 1 and NF-kappaB-inducing kinase

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

MEKK1 activates both IkappaB kinase alpha and IkappaB kinase beta

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

Mitogen-activated protein kinase/ERK kinase kinases 2 and 3 activate nuclear factor-kappaB through IkappaB kinase-alpha and IkappaB kinase-beta

Positive and negative regulation of IkappaB kinase activity through IKKbeta subunit phosphorylation

Phylogenetic perspectives in innate immunity

P304

15854-15860

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.M100010200

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

276

http://www.w3.org/2001/XMLSchema#string

P577

2001-02-09T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

11278990

http://www.w3.org/2001/XMLSchema#string

Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

about

P2860

P2860

Inhibition of the nuclear factor kappa B (NF-kappa B) pathway by tetracyclic kaurene diterpenes in macrophages. Specific effects on NF-kappa B-inducing kinase activity and on the coordinate activation of ERK and p38 MAPK.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P698