Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels.
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Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytesThe phosphatidylinositol 3-phosphate phosphatase myotubularin- related protein 6 (MTMR6) is a negative regulator of the Ca2+-activated K+ channel KCa3.1STIM1 is a Ca2+ sensor that activates CRAC channels and migrates from the Ca2+ store to the plasma membraneSelective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosisGlutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosisImaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block.The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humansPhosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cellsThe voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MSObstructing toxin pathways by targeted pore blockageIon channels and transporters in lymphocyte function and immunityComputational properties of mitochondria in T cell activation and fateSK channels and ventricular arrhythmias in heart failureDelineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1Potassium channel-blockers as therapeutic agents to interfere with bone resorption of periodontal diseaseCa(2+)-activated K+ channels: molecular determinants and function of the SK familyMolecular and cellular basis of small--and intermediate-conductance, calcium-activated potassium channel function in the brain.Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow.Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent mannerNuclear localization and dominant-negative suppression by a mutant SKCa3 N-terminal channel fragment identified in a patient with schizophrenia.Cloning and identification of tissue-specific expression of KCNN4 splice variants in rat colon.Novel truncated isoform of SK3 potassium channel is a potent dominant-negative regulator of SK currents: implications in schizophrenia.Maternal diabetes increases small conductance Ca2+-activated K+ (SK) currents that alter action potential properties and excitability of cardiac motoneurons in the nucleus ambiguusSK3-1C, a dominant-negative suppressor of SKCa and IKCa channels.Phosphatidylinositol 3-phosphate indirectly activates KCa3.1 via 14 amino acids in the carboxy terminus of KCa3.1.Selective activation of KCa3.1 and CRAC channels by P2Y2 receptors promotes Ca(2+) signaling, store refilling and migration of rat microglial cellsPotent suppression of Kv1.3 potassium channel and IL-2 secretion by diphenyl phosphine oxide-1 in human T cells.Involvement of dominant-negative spliced variants of the intermediate conductance Ca2+-activated K+ channel, K(Ca)3.1, in immune function of lymphoid cellsA small conductance calcium-activated K+ channel in C. elegans, KCNL-2, plays a role in the regulation of the rate of egg-layingThe K+ channel KCa3.1 as a novel target for idiopathic pulmonary fibrosisHuman lung myofibroblast TGFβ1-dependent Smad2/3 signalling is Ca(2+)-dependent and regulated by KCa3.1 K(+) channelsPhysiological epidermal growth factor concentrations activate high affinity receptors to elicit calcium oscillations.High expression of KCa3.1 in patients with clear cell renal carcinoma predicts high metastatic risk and poor survival.Density of functional Ca2+ release-activated Ca2+ (CRAC) channels declines after T-cell activation.Detailed examination of Mg2+ and pH sensitivity of human TRPM7 channels.Trafficking of intermediate (KCa3.1) and small (KCa2.x) conductance, Ca(2+)-activated K(+) channels: a novel target for medicinal chemistry efforts?Anti-inflammatory effects of kinins via microglia in the central nervous system.Altered dynamics of Kv1.3 channel compartmentalization in the immunological synapse in systemic lupus erythematosusIon channels in innate and adaptive immunityInhibiting bacterial toxins by channel blockage.
P2860
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P2860
Calcium-activated potassium channels sustain calcium signaling in T lymphocytes. Selective blockers and manipulated channel expression levels.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Calcium-activated potassium ch ...... ted channel expression levels.
@en
type
label
Calcium-activated potassium ch ...... ted channel expression levels.
@en
prefLabel
Calcium-activated potassium ch ...... ted channel expression levels.
@en
P2093
P2860
P356
P1476
Calcium-activated potassium ch ...... ted channel expression levels.
@en
P2093
Cahalan MD
Ganellin CR
P2860
P304
12249-12256
P356
10.1074/JBC.M011342200
P407
P577
2001-01-22T00:00:00Z