Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
about
Viral immune modulators perturb the human molecular network by common and unique strategiesHepatitis C virus non-structural protein NS5A interacts with FKBP38 and inhibits apoptosis in Huh7 hepatoma cellsDisruption of Bcl-2 and Bcl-xL by viral proteins as a possible cause of cancerHepatitis C Virus Induces E6AP-Dependent Degradation of the Retinoblastoma ProteinAltered expression of cell cycle and apoptotic proteins in chronic hepatitis C virus infectionActivation of Ribosomal RNA Transcription by Hepatitis C Virus Involves Upstream Binding Factor Phosphorylation via Induction of Cyclin D1Hepatitis C Virus NS5A Protein Down-regulates the Expression of Spindle Gene Aspm through PKR-p38 Signaling PathwayUltradeep sequencing study of chronic hepatitis C virus genotype 1 infection in patients treated with daclatasvir, peginterferon, and ribavirin.Hepatitis C virus NS5B protein delays s phase progression in human hepatocyte-derived cells by relocalizing cyclin-dependent kinase 2-interacting protein (CINP).Hepatitis C virus NS5A activates the mammalian target of rapamycin (mTOR) pathway, contributing to cell survival by disrupting the interaction between FK506-binding protein 38 (FKBP38) and mTORHepatitis C virus biology.Hepatitis C and liver fibrosis.Molecular viral oncology of hepatocellular carcinoma.Hepatocyte Turnover in Chronic HCV-Induced Liver Injury and Cirrhosis.Virus-host cell interactions during hepatitis C virus RNA replication: impact of polyprotein expression on the cellular transcriptome and cell cycle association with viral RNA synthesis.Tumor suppressors, chromosomal instability, and hepatitis C virus-associated liver cancer.Pathogenesis and prevention of hepatitis C virus-induced hepatocellular carcinoma.Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation.Hepatitis C virus-induced hepatocellular carcinomaHost cell targets in HCV therapy: novel strategy or proven practice?HCV NS5A abrogates p53 protein function by interfering with p53-DNA binding.Regulation of hepatitis C virus replication by nuclear translocation of nonstructural 5A protein and transcriptional activation of host genes.How Hepatitis C Virus Leads to Hepatocellular Carcinoma: A Network-Based Study.Hepatitis C virus: from oxygen free radicals to hepatocellular carcinoma.Viral transformation and aneuploidy.Residual risk of hepatocellular carcinoma after HCV eradication: more than meets the eye.A unique phosphorylation-dependent eIF4E assembly on 40S ribosomes co-ordinated by hepatitis C virus protein NS5A that activates internal ribosome entry site translation.NS5ATP9 contributes to inhibition of cell proliferation by hepatitis C virus (HCV) nonstructural protein 5A (NS5A) via MEK/extracellular signal regulated kinase (ERK) pathway.Hepatitis C virus core protein induces apoptosis-like caspase independent cell death.TARGETING THE NS5A PROTEIN OF HCV: AN EMERGING OPTION.Calcium-dependent calpain proteases are implicated in processing of the hepatitis C virus NS5A protein.Site-specific mutation of the interferon sensitivity-determining region (ISDR) modulates hepatitis C virus replication.The NS5A protein of the hepatitis C virus genotype 1a is cleaved by caspases to produce C-terminal-truncated forms of the protein that reside mainly in the cytosol.Nonstructural protein 5B promotes degradation of the NORE1A tumor suppressor to facilitate hepatitis C virus replication.Efficient rescue of hepatitis C virus RNA replication by trans-complementation with nonstructural protein 5A.Modulation of p53 transcription regulatory activity and post-translational modification by hepatitis C virus core protein.The hepatitis C virus non-structural NS5A protein inhibits activating protein-1 function by perturbing ras-ERK pathway signaling.Emergence of resistant variants detected by ultra-deep sequencing after asunaprevir and daclatasvir combination therapy in patients infected with hepatitis C virus genotype 1.Characteristic sequence changes of hepatitis C virus genotype 2b associated with sustained biochemical response to IFN therapy.Is investigation of hepatitis C virus NS5A gene heterogeneity a tool for predicting long-lasting response to interferon therapy in patients with HCV-1b chronic hepatitis?
P2860
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P2860
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
@en
type
label
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
@en
prefLabel
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
@en
P2093
P2860
P356
P1476
Modulation of cell growth by the hepatitis C virus nonstructural protein NS5A.
@en
P2093
P2860
P304
12675-12684
P356
10.1074/JBC.M008329200
P407
P577
2001-01-19T00:00:00Z