The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.
about
NF1 mutations and molecular testingMast cells and the neurofibroma microenvironmentComplete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirusPremature ligand-receptor interaction during biosynthesis limits the production of growth factor midkine and its receptor LDL receptor-related protein 1Analysis of steroid hormone effects on xenografted human NF1 tumor schwann cellsAntiangiogenesis in neurofibromatosis 1.Genetic and functional studies implicate synaptic overgrowth and ring gland cAMP/PKA signaling defects in the Drosophila melanogaster neurofibromatosis-1 growth deficiency.Perinatal epidermal growth factor receptor blockade prevents peripheral nerve disruption in a mouse model reminiscent of benign world health organization grade I neurofibromaAngiogenic factors in the central nervous system.A novel cytokine pathway suppresses glial cell melanogenesis after injury to adult nerve.Midkine: a promising molecule for drug development to treat diseases of the central nervous systemMolecular characterization of human meningiomas by gene expression profiling using high-density oligonucleotide microarrays.Pigment cell-related manifestations in neurofibromatosis type 1: an overview.Tumor suppressor mutations and growth factor signaling in the pathogenesis of NF1-associated peripheral nerve sheath tumors: II. The role of dysregulated growth factor signaling.Pediatric cancer gone viral. Part II: potential clinical application of oncolytic herpes simplex virus-1 in children.Midkine, a heparin-binding cytokine with multiple roles in development, repair and diseases.Partial Blindness to Submicron Topography in NF1 Haploinsufficient Cultured Fibroblasts Indicates a New Function of Neurofibromin in Regulation of Mechanosensoric.Midkine promoter-based conditionally replicative adenovirus therapy for midkine-expressing human pancreatic cancer.Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas.Pathogenesis of plexiform neurofibroma: tumor-stromal/hematopoietic interactions in tumor progression.Midkine: a novel prognostic biomarker for cancer.Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033.Therapeutic potential of midkine in cardiovascular disease.Progress of oncolytic viruses in sarcomas.Midkine in repair of the injured nervous systemIncreased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target.Midkine is associated with neuroendocrine differentiation in castration-resistant prostate cancer.Oncolytic virotherapy for osteosarcoma using midkine promoter-regulated adenoviruses.Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma.Sensitization of lung cancer cells to cisplatin by β-elemene is mediated through blockade of cell cycle progression: antitumor efficacies of β-elemene and its synthetic analogs.Chronic smoking and alcoholism change expression of selective genes in the human prefrontal cortex.Gene expression analysis identifies potential biomarkers of neurofibromatosis type 1 including adrenomedullin.Circulating IGF-1 deficiency exacerbates hypertension-induced microvascular rarefaction in the mouse hippocampus and retrosplenial cortex: implications for cerebromicrovascular and brain aging.Midkine Mediates Intercellular Crosstalk between Drug-Resistant and Drug-Sensitive Neuroblastoma Cells In Vitro and In Vivo.Overexpression of PDGFRA cooperates with loss of NF1 and p53 to accelerate the molecular pathogenesis of malignant peripheral nerve sheath tumors.A Drosophila screen identifies neurofibromatosis-1 genetic modifiers involved in systemic and synaptic growth.Serum levels of fibroblast growth factor 2 in children with orthopedic diseases: potential role in predicting bone healing.Expression of angiogenic factors in neurofibromas.Midkine in inflammation.
P2860
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P2860
The angiogenic factor midkine is aberrantly expressed in NF1-deficient Schwann cells and is a mitogen for neurofibroma-derived cells.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The angiogenic factor midkine ...... or neurofibroma-derived cells.
@en
type
label
The angiogenic factor midkine ...... or neurofibroma-derived cells.
@en
prefLabel
The angiogenic factor midkine ...... or neurofibroma-derived cells.
@en
P2093
P2860
P356
P1433
P1476
The angiogenic factor midkine ...... for neurofibroma-derived cells
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204026
P407
P577
2001-01-01T00:00:00Z
P5875
P6179
1028055471