Structural and kinetic determinants of aldehyde reduction by aldose reductase.
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Aldehyde dehydrogenase inhibition generates a reactive dopamine metabolite autotoxic to dopamine neuronsExpression and activities of aldo-keto oxidoreductases in Alzheimer diseaseStructural and kinetic modifications of aldose reductase by S-nitrosothiolsIdentification of biochemical pathways for the metabolism of oxidized low-density lipoprotein derived aldehyde-4-hydroxy trans-2-nonenal in vascular smooth muscle cellsA potential therapeutic role for aldose reductase inhibitors in the treatment of endotoxin-related inflammatory diseasesArsenic and cardiovascular diseaseMitogenic responses of vascular smooth muscle cells to lipid peroxidation-derived aldehyde 4-hydroxy-trans-2-nonenal (HNE): role of aldose reductase-catalyzed reduction of the HNE-glutathione conjugates in regulating cell growthRedox activation of aldose reductase in the ischemic heartProtein modification by acrolein: formation and stability of cysteine adductsBiological Chemistry and Functionality of Protein Sulfenic Acids and Related Thiol ModificationsMechanisms of acrolein-induced myocardial dysfunction: implications for environmental and endogenous aldehyde exposure.Aldo-keto reductase family 1 member B8 is secreted via non-classical pathway.Postischemic deactivation of cardiac aldose reductase: role of glutathione S-transferase P and glutaredoxin in regeneration of reduced thiols from sulfenic acidsALDOSE REDUCTASE: New Insights for an Old Enzyme.A new approach to control the enigmatic activity of aldose reductase.Human aldo-keto reductases 1B1 and 1B10: a comparative study on their enzyme activity toward electrophilic carbonyl compounds.Characterization of two distinct structural classes of selective aldehyde dehydrogenase 1A1 inhibitors.Aldose reductase decreases endoplasmic reticulum stress in ischemic hearts.Oxidative and reductive metabolism of lipid-peroxidation derived carbonyls.Detoxification of aldehydes by histidine-containing dipeptides: from chemistry to clinical implicationsAldose reductase deficiency in mice protects from ragweed pollen extract (RWE)-induced allergic asthma.Aldose reductase and AGE-RAGE pathways: key players in myocardial ischemic injury.Aldose reductase-catalyzed reduction of aldehyde phospholipidsAldehyde sources, metabolism, molecular toxicity mechanisms, and possible effects on human health.Glutathione level regulates HNE-induced genotoxicity in human erythroleukemia cells.Mechanisms linking diabetes mellitus to the development of atherosclerosis: a role for endoplasmic reticulum stress and glycogen synthase kinase-3.Aldose reductase protects against early atherosclerotic lesion formation in apolipoprotein E-null mice.Aldo-keto reductase 1 family B7 is the gene induced in response to oxidative stress in the livers of Long-Evans Cinnamon rats.Aldehyde metabolism in the cardiovascular system.Protein functional surfaces: global shape matching and local spatial alignments of ligand binding sites.Interaction of aldehydes derived from lipid peroxidation and membrane proteinsDetoxification reactions: relevance to aging.Role of aldose reductase in the metabolism and detoxification of carnosine-acrolein conjugates.Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue.Aldose reductase: a novel therapeutic target for inflammatory pathologies.Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model.Understanding the role of aldose reductase in ocular inflammation.Protein modification by acrolein: relevance to pathological conditions and inhibition by aldehyde sequestering agents.Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.Development of aldose reductase inhibitors for the treatment of inflammatory disorders.
P2860
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P2860
Structural and kinetic determinants of aldehyde reduction by aldose reductase.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Structural and kinetic determinants of aldehyde reduction by aldose reductase.
@en
type
label
Structural and kinetic determinants of aldehyde reduction by aldose reductase.
@en
prefLabel
Structural and kinetic determinants of aldehyde reduction by aldose reductase.
@en
P2093
P356
P1433
P1476
Structural and kinetic determinants of aldehyde reduction by aldose reductase.
@en
P2093
A Bhatnagar
J M Petrash
S J Watowich
S K Srivastava
S Srivastava
P356
10.1021/BI981794L
P407
P577
1999-01-01T00:00:00Z