Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1).
about
A region within a lumenal loop of Saccharomyces cerevisiae Ycf1p directs proteolytic processing and substrate specificity.Cloning and characterization of the rat multidrug resistance-associated protein 1Role of the N-terminal transmembrane domain in the endo-lysosomal targeting and function of the human ABCB6 protein.Targeting the Achilles heel of multidrug-resistant cancer by exploiting the fitness cost of resistance.Requirement of the N-terminal extension for vacuolar trafficking and transport activity of yeast Ycf1p, an ATP-binding cassette transporter.Multidrug resistance protein 1 (MRP1, ABCC1), a "multitasking" ATP-binding cassette (ABC) transporter.Mechanism of KATP hyperactivity and sulfonylurea tolerance due to a diabetogenic mutation in L0 helix of sulfonylurea receptor 1 (ABCC8)Casein kinase 2α regulates multidrug resistance-associated protein 1 function via phosphorylation of Thr249.Virtual screening of ABCC1 transporter nucleotidebinding domains as a therapeutic target in multidrug resistant cancer.Targeted delivery of doxorubicin through conjugation with EGF receptor-binding peptide overcomes drug resistance in human colon cancer cells.Effect of cysteine mutagenesis on the function and disulfide bond formation of human ABCG2.ABC transporters in Saccharomyces cerevisiae and their interactors: new technology advances the biology of the ABCC (MRP) subfamily.Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating.Suppression of Ycf1p function by Cka1p-dependent phosphorylation is attenuated in response to salt stress.Negative regulation of the yeast ABC transporter Ycf1p by phosphorylation within its N-terminal extension.Three C-terminal residues from the sulphonylurea receptor contribute to the functional coupling between the K(ATP) channel subunits SUR2A and Kir6.2.Targeting Nucleotide Binding Domain of Multidrug Resistance-associated Protein-1 (MRP1) for the Reversal of Multi Drug Resistance in Cancer
P2860
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P2860
Characterization of the amino-terminal regions in the human multidrug resistance protein (MRP1).
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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name
Characterization of the amino- ...... rug resistance protein (MRP1).
@en
type
label
Characterization of the amino- ...... rug resistance protein (MRP1).
@en
prefLabel
Characterization of the amino- ...... rug resistance protein (MRP1).
@en
P2093
P1476
Characterization of the amino- ...... drug resistance protein (MRP1)
@en
P2093
P304
P407
P478
P577
2000-12-01T00:00:00Z