Packaging cell line characteristics and optimizing retroviral vector titer: the National Gene Vector Laboratory experience.
about
Retroviral vectors for clinical immunogene therapy are stable for up to 9 years.Scale-up and manufacturing of clinical-grade self-inactivating γ-retroviral vectors by transient transfectionRapid production of clinical-grade gammaretroviral vectors in expanded surface roller bottles using a "modified" step-filtration process for clearance of packaging cells.Large-scale clinical-grade retroviral vector production in a fixed-bed bioreactor.Genetic modification of human hematopoietic cells: preclinical optimization of oncoretroviral-mediated gene transfer for clinical trialsPredicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy.Enhanced receptor expression and in vitro effector function of a murine-human hybrid MART-1-reactive T cell receptor following a rapid expansionRetroviral vector production in the National Gene Vector Laboratory at Indiana University.Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free media.Post-mitotic, differentiated myotubes efficiently produce retroviral vector from hybrid adeno-retrovirus templates.Clinical retroviral vector production: step filtration using clinically approved filters improves titers.
P2860
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P2860
Packaging cell line characteristics and optimizing retroviral vector titer: the National Gene Vector Laboratory experience.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
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name
Packaging cell line characteri ...... Vector Laboratory experience.
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type
label
Packaging cell line characteri ...... Vector Laboratory experience.
@en
prefLabel
Packaging cell line characteri ...... Vector Laboratory experience.
@en
P2093
P1433
P1476
Packaging cell line characteri ...... Vector Laboratory experience.
@en
P2093
P304
P356
10.1089/104303400750001408
P577
2000-10-01T00:00:00Z