Membrane association and targeting of prenylated Ras-like GTPases.
about
Rac3-induced neuritogenesis requires binding to Neurabin IStructure of mammalian protein geranylgeranyltransferase type-IEndogenous, hyperactive Rac3 controls proliferation of breast cancer cells by a p21-activated kinase-dependent pathwayLipid Raft targeting of the TC10 amino terminal domain is responsible for disruption of adipocyte cortical actinRapid degradation of dominant-negative Rab27 proteins in vivo precludes their use in transgenic mouse models.Role of substrate dynamics in protein prenylation reactionsCrystal structure of Sar1-GDP at 1.7 Å resolution and the role of the NH 2 terminus in ER exportDual prenylation is required for Rab protein localization and functionPrenylation-dependent association of protein-tyrosine phosphatases PRL-1, -2, and -3 with the plasma membrane and the early endosomeInteraction of farnesylated PRL-2, a protein-tyrosine phosphatase, with the beta-subunit of geranylgeranyltransferase IIRab geranylgeranyl transferase alpha mutation in the gunmetal mouse reduces Rab prenylation and platelet synthesisMicrocephaly-dystonia due to mutated PLEKHG2 with impaired actin polymerization.Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation.Rab3D regulates a novel vesicular trafficking pathway that is required for osteoclastic bone resorption.A novel statin-mediated "prenylation block-and-release" assay provides insight into the membrane targeting mechanisms of small GTPases.RacF1, a novel member of the Rho protein family in Dictyostelium discoideum, associates transiently with cell contact areas, macropinosomes, and phagosomes.In vivo antitumor effect of a novel inhibitor of protein geranylgeranyltransferase-IRac1 dynamics in the human opportunistic fungal pathogen Candida albicansThe small GTPase RhoA localizes to the nucleus and is activated by Net1 and DNA damage signalsThe alpha-subunit of protein prenyltransferases is a member of the tetratricopeptide repeat family.Genetic analysis of lysosomal trafficking in Caenorhabditis elegansEnlarging the scope of cell-penetrating prenylated peptides to include farnesylated 'CAAX' box sequences and diverse cell types.The function of two Rho family GTPases is determined by distinct patterns of cell surface localizationOrganization of the Rab-GDI/CHM superfamily: the functional basis for choroideremia disease.The adaptor protein Bam32 regulates Rac1 activation and actin remodeling through a phosphorylation-dependent mechanism.Increased RhoA prenylation in the loechrig (loe) mutant leads to progressive neurodegenerationProteomic analysis of rhoptry organelles reveals many novel constituents for host-parasite interactions in Toxoplasma gondii.Genetic interactions between the RhoA and Stubble-stubbloid loci suggest a role for a type II transmembrane serine protease in intracellular signaling during Drosophila imaginal disc morphogenesis.Targeting mutant KRAS for anticancer therapeutics: a review of novel small molecule modulators.Thy-1-induced migration inhibition in vascular endothelial cells through reducing the RhoA activityMurine guanylate-binding protein: incomplete geranylgeranyl isoprenoid modification of an interferon-gamma-inducible guanosine triphosphate-binding proteinProtein prenylation: enzymes, therapeutics, and biotechnology applications.Function and regulation of Rnd proteins in cortical projection neuron migrationIncreased actin polymerization and stabilization interferes with neuronal function and survival in the AMPKγ mutant Loechrig.Membrane targeting of Rab GTPases is influenced by the prenylation motifRho GTPases as therapeutic targets for the treatment of inflammatory diseases.Annexin 2 regulates intestinal epithelial cell spreading and wound closure through Rho-related signaling.Vesicle and vesicle-free extracellular proteome of Paracoccidioides brasiliensis: comparative analysis with other pathogenic fungi.Detection and Quantification of ADP-Ribosylated RhoA/B by Monoclonal Antibody.Lipid-lowering drugs.
P2860
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P2860
Membrane association and targeting of prenylated Ras-like GTPases.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Membrane association and targeting of prenylated Ras-like GTPases.
@en
type
label
Membrane association and targeting of prenylated Ras-like GTPases.
@en
prefLabel
Membrane association and targeting of prenylated Ras-like GTPases.
@en
P1433
P1476
Membrane association and targeting of prenylated Ras-like GTPases.
@en
P304
P356
10.1016/S0898-6568(97)00120-4
P577
1998-03-01T00:00:00Z