Aryloxypropanolamine and catecholamine ligand interactions with the beta(1)-adrenergic receptor: evidence for interaction with distinct conformations of beta(1)-adrenergic receptors.
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Antagonist affinity measurements at the Gi-coupled human histamine H3 receptor expressed in CHO cellsA full pharmacological analysis of the three turkey β-adrenoceptors and comparison with the human β-adrenoceptorsIdentification of key residues in transmembrane 4 responsible for the secondary, low-affinity conformation of the human β1-adrenoceptorEvolution of β-blockers: from anti-anginal drugs to ligand-directed signalling.Role of β-adrenoceptors in glucose uptake in astrocytes using β-adrenoceptor knockout mice.Overexpression of beta 1-adrenoceptors in adult rat ventricular myocytes enhances CGP 12177A cardiostimulation: implications for 'putative' beta 4-adrenoceptor pharmacologyImpact of polymorphic variants on the molecular pharmacology of the two-agonist conformations of the human β1-adrenoceptor.Impairment of the low-affinity state beta1-adrenoceptor-induced relaxation in spontaneously hypertensive ratsMultiple GPCR conformations and signalling pathways: implications for antagonist affinity estimates.Chronic activation of the low affinity site of β1-adrenoceptors stimulates haemodynamics but exacerbates pressure-overload cardiac remodelling.Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricleUse of a new proximity assay (NanoBRET) to investigate the ligand-binding characteristics of three fluorescent ligands to the human β1-adrenoceptor expressed in HEK-293 cells.Metabolic responses to BRL37344 and clenbuterol in soleus muscle and C2C12 cells via different atypical pharmacologies and beta2-adrenoceptor mechanismsA study of antagonist affinities for the human histamine H2 receptor.Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist.Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation.Detection of the secondary, low-affinity β1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP.The pharmacological effects of the thermostabilising (m23) mutations and intra and extracellular (β36) deletions essential for crystallisation of the turkey β-adrenoceptor.Positive inotropic and lusitropic effects mediated via the low-affinity state of beta1-adrenoceptors in pithed rats.Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor.Comparison of the affinity of beta-blockers for two states of the beta 1-adrenoceptor in ferret ventricular myocardium.
P2860
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P2860
Aryloxypropanolamine and catecholamine ligand interactions with the beta(1)-adrenergic receptor: evidence for interaction with distinct conformations of beta(1)-adrenergic receptors.
description
2000 nî lūn-bûn
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Aryloxypropanolamine and catec ...... beta(1)-adrenergic receptors.
@en
type
label
Aryloxypropanolamine and catec ...... beta(1)-adrenergic receptors.
@en
prefLabel
Aryloxypropanolamine and catec ...... beta(1)-adrenergic receptors.
@en
P2093
P1476
Aryloxypropanolamine and catec ...... f beta(1)-adrenergic receptors
@en
P2093
P304
P407
P577
2000-09-01T00:00:00Z