Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules.
about
Association of tapasin and COPI provides a mechanism for the retrograde transport of major histocompatibility complex (MHC) class I molecules from the Golgi complex to the endoplasmic reticulumWhat is the role of alternate splicing in antigen presentation by major histocompatibility complex class I molecules?Immunoproteomics: Mass spectrometry-based methods to study the targets of the immune responseTapasin enhances MHC class I peptide presentation according to peptide half-lifeDifferential expression of tapasin and immunoproteasome subunits in adenovirus type 5- versus type 12-transformed cellsThe binding of TAPBPR and Tapasin to MHC class I is mutually exclusive.TAPBPR isoforms exhibit altered association with MHC class I.The convergent roles of tapasin and HLA-DM in antigen presentation.Dissecting the role of peptides in the immune response: theory, practice and the application to vaccine design.Direct peptide-regulatable interactions between MHC class I molecules and tapasin.Analysis of major histocompatibility complex class I folding: novel insights into intermediate formsAssociation of antigen processing machinery and HLA class I defects with clinicopathological outcome in cervical carcinoma.HLA class I transgenic mice: development, utilisation and improvement.Dynamics of major histocompatibility complex class I association with the human peptide-loading complex.Accessory molecules in the assembly of major histocompatibility complex class I/peptide complexes: how essential are they for CD8(+) T-cell immune responses?The optimization of peptide cargo bound to MHC class I molecules by the peptide-loading complex.Recognition of open conformers of classical MHC by chaperones and monoclonal antibodies.Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasionMechanisms of Disease: the immunopathogenesis of spondyloarthropathies.The double role of the endoplasmic reticulum chaperone tapasin in peptide optimization of HLA class I molecules.Peptide induction of surface expression of class I MHC.Redox-regulated export of the major histocompatibility complex class I-peptide complexes from the endoplasmic reticulumAnalysis of interactions in a tapasin/class I complex provides a mechanism for peptide selection.Understanding the obstacle of incompatibility at residue 156 within HLA-B*35 subtypes.Influence of the tapasin C terminus on the assembly of MHC class I allotypes.Conformational flexibility of the MHC class I alpha1-alpha2 domain in peptide bound and free states: a molecular dynamics simulation study.Functional dissection of the transmembrane domains of the transporter associated with antigen processing (TAP).Species-specific differences in proteasomal processing and tapasin-mediated loading influence peptide presentation by HLA-B27 in murine cells.Mutant MHC class I molecules define interactions between components of the peptide-loading complex.Mutational analysis reveals a complex interplay of peptide binding and multiple biological features of HLA-B27.The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I.
P2860
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P2860
Tapasin-mediated retention and optimization of peptide ligands during the assembly of class I molecules.
description
2000 nî lūn-bûn
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2000年の論文
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2000年学术文章
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2000年学术文章
@zh-cn
2000年学术文章
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2000年学术文章
@zh-my
2000年学术文章
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2000年學術文章
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2000年學術文章
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2000年學術文章
@zh-hant
name
Tapasin-mediated retention and ...... assembly of class I molecules.
@en
type
label
Tapasin-mediated retention and ...... assembly of class I molecules.
@en
prefLabel
Tapasin-mediated retention and ...... assembly of class I molecules.
@en
P2093
P1476
Tapasin-mediated retention and ...... assembly of class I molecules.
@en
P2093
Barnden MJ
McCluskey J
P304
P356
10.4049/JIMMUNOL.165.1.322
P407
P577
2000-07-01T00:00:00Z