Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis.

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PBPK modeling and simulation in drug research and development Pharmacometric Approaches to Personalize Use of Primarily Renally Eliminated Antibiotics in Preterm and Term Neonates.Evaluation of Model-Based Prediction of Pharmacokinetics in the Renal Impairment Population.

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P2860

Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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Physiologically based and popu ...... redict-learn-confirm analysis.

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Physiologically based and popu ...... redict-learn-confirm analysis.

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Physiologically based and popu ...... redict-learn-confirm analysis.

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P1476

Physiologically based and popu ...... redict-learn-confirm analysis.

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P2860

Towards quantitation of the effects of renal impairment and probenecid inhibition on kidney uptake and efflux transporters, using physiologically based pharmacokinetic modelling and simulations

Prediction of creatinine clearance from serum creatinine

Phase 1/2 study of orteronel (TAK-700), an investigational 17,20-lyase inhibitor, with docetaxel-prednisone in metastatic castration-resistant prostate cancer.

Phase III, randomized, double-blind, multicenter trial comparing orteronel (TAK-700) plus prednisone with placebo plus prednisone in patients with metastatic castration-resistant prostate cancer that has progressed during or after docetaxel-based th

Physiologically-based pharmacokinetics in drug development and regulatory science.

Applications of physiologically based pharmacokinetic (PBPK) modeling and simulation during regulatory review.

Modeling and predicting drug pharmacokinetics in patients with renal impairment.

Utility of a physiologically-based pharmacokinetic (PBPK) modeling approach to quantitatively predict a complex drug-drug-disease interaction scenario for rivaroxaban during the drug review process: implications for clinical practice.

Emerging areas of research in the assessment of pharmacokinetics in patients with chronic kidney disease.

Dealing with the complex drug-drug interactions: towards mechanistic models.

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336-344

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scholarly article

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10.1002/CPT.155

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English

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2015-06-01T00:00:00Z

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Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis.

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P2860

P2860

Physiologically based and population PK modeling in optimizing drug development: A predict-learn-confirm analysis.

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type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P932