A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies.
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A mouse model of pulmonary metastasis from spontaneous osteosarcoma monitored in vivo by Luciferase imaging.Immunotherapy for osteosarcoma: genetic modification of T cells overcomes low levels of tumor antigen expression.Establishment and characterization of a new highly metastatic human osteosarcoma cell line derived from Saos2.Inhalation delivery and anti-tumor activity of celecoxib in human orthotopic non-small cell lung cancer xenograft modelFas expression in metastatic osteosarcoma cells is not regulated by CpG island methylationNatural killer cell therapy and aerosol interleukin-2 for the treatment of osteosarcoma lung metastasis.The cyclin-dependent kinase inhibitor SCH 727965 (dinacliclib) induces the apoptosis of osteosarcoma cellsA systems biology approach reveals common metastatic pathways in osteosarcoma.Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing's sarcoma in the lung.Aerosol therapy for the treatment of osteosarcoma lung metastases: targeting the Fas/FasL pathway and rationale for the use of gemcitabine.Effect of the histone deacetylase inhibitor SNDX-275 on Fas signaling in osteosarcoma cells and the feasibility of its topical application for the treatment of osteosarcoma lung metastasesPolyethyleneimine-based gene therapy by inhalation.Sox2 antagonizes the Hippo pathway to maintain stemness in cancer cellsGenomic instability of osteosarcoma cell lines in culture: impact on the prediction of metastasis relevant genes.miR-20a encoded by the miR-17-92 cluster increases the metastatic potential of osteosarcoma cells by regulating Fas expression.Corruption of the Fas pathway delays the pulmonary clearance of murine osteosarcoma cells, enhances their metastatic potential, and reduces the effect of aerosol gemcitabine.Osteosarcoma Phenotype Is Inhibited by 3,4-Methylenedioxy-β-nitrostyreneMS-275 sensitizes osteosarcoma cells to Fas ligand-induced cell death by increasing the localization of Fas in membrane lipid rafts.Osteosarcoma cell proliferation and survival requires mGluR5 receptor activity and is blocked by Riluzole.The effect of bone morphogenetic protein-2 on osteosarcoma metastasis.Genes regulated in metastatic osteosarcoma: evaluation by microarray analysis in four human and two mouse cell line systems.Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell linesAnoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesisCharacterization of the metastatic phenotype of a panel of established osteosarcoma cells.Evolving gene therapy approaches for osteosarcoma using viral vectors: reviewChanges in cell shape are correlated with metastatic potential in murine and human osteosarcomas.Non-viral methods for gene transfer towards osteosarcoma therapy.Specific tyrosine kinase inhibitors regulate human osteosarcoma cells in vitro.Metastatic osteosarcoma gene expression differs in vitro and in vivoVEGF165 is necessary to the metastatic potential of Fas(-) osteosarcoma cells but will not rescue the Fas(+) cellsTargeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin.p27 Is a Candidate Prognostic Biomarker and Metastatic Promoter in Osteosarcoma.Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery.Mitochondrial dysfunction and permeability transition in osteosarcoma cells showing the Warburg effect.Genetically modified T cells targeting interleukin-11 receptor α-chain kill human osteosarcoma cells and induce the regression of established osteosarcoma lung metastases.Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs.Animal models of osteosarcoma.Preclinical models for pediatric solid tumor drug discovery: current trends, challenges and the scopes for improvement.BMTP-11 is active in preclinical models of human osteosarcoma and a candidate targeted drug for clinical translation.miR-27a and miR-27a* contribute to metastatic properties of osteosarcoma cells
P2860
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P2860
A nude mouse model of human osteosarcoma lung metastases for evaluating new therapeutic strategies.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
A nude mouse model of human os ...... ng new therapeutic strategies.
@en
type
label
A nude mouse model of human os ...... ng new therapeutic strategies.
@en
prefLabel
A nude mouse model of human os ...... ng new therapeutic strategies.
@en
P2093
P4510
P356
P1476
A nude mouse model of human os ...... ng new therapeutic strategies.
@en
P2093
P2888
P304
P356
10.1023/A:1006623001465
P577
1999-01-01T00:00:00Z
P6179
1017353406