The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis.

The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis.

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http://www.wikidata.org/entity/Q40895418
NETosis as Source of Autoantigens in Rheumatoid ArthritisNegative regulation of TLR signaling in myeloid cells--implications for autoimmune diseases.A molecular signature of preclinical rheumatoid arthritis triggered by dysregulated PTPN22B Cell Tolerance to Deiminated Histones in BALB/c, C57BL/6, and Autoimmune-Prone Mouse Strains.The Genotype and Phenotype (GaP) registry: a living biobank for the analysis of quantitative traits.Joint inflammation related citrullination of functional arginines in extracellular proteins.Citrullination of NF-κB p65 promotes its nuclear localization and TLR-induced expression of IL-1β and TNFα.The PTPN22 R263Q polymorphism confers protection against systemic lupus erythematosus and rheumatoid arthritis, while PTPN22 R620W confers susceptibility to Graves' disease in a Mexican population.Review: Neutrophils as Invigorated Targets in Rheumatic DiseasesDisentangling the role of neutrophil extracellular traps in rheumatic diseases.Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.An emerging role for neutrophil extracellular traps in noninfectious disease.The functional PTPN22 C1858T polymorphism confers risk for rheumatoid arthritis in patients from Central Mexico.Activation of Peptidylarginine Deiminase in the Salivary Glands of Balb/c Mice Drives the Citrullination of Ro and La Ribonucleoproteins.Genetic and environmental risk factors for rheumatoid arthritis.The Protein Tyrosine Phosphatase Nonreceptor 22 (PTPN22) R620W Functional Polymorphism in Psoriasis.
P2860

The W620 Polymorphism in PTPN22 Disrupts Its Interaction With Peptidylarginine Deiminase Type 4 and Enhances Citrullination and NETosis.

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http://www.wikidata.org/entity/Q40895418
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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The W620 Polymorphism in PTPN2 ...... es Citrullination and NETosis.
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type
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The W620 Polymorphism in PTPN2 ...... es Citrullination and NETosis.
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The W620 Polymorphism in PTPN2 ...... es Citrullination and NETosis.
@en
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698
P356
P1433
P1476
The W620 Polymorphism in PTPN2 ...... es Citrullination and NETosis.
@en
P2093
P2860
P304
P31
P356
P433
P478
P50
P577
P698