Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein.
about
Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformationDeletion analysis and alternative splicing define a transactivation inhibitory domain in human oncoprotein RELNF-kappaB2 mutation targets TRAF1 to induce lymphomagenesis.Constitutive production of NF-kappaB2 p52 is not tumorigenic but predisposes mice to inflammatory autoimmune disease by repressing Bim expression.NFκB function and regulation in cutaneous T-cell lymphoma.Matrix Metalloproteinase-9 gene induction by a truncated oncogenic NF-kappaB2 protein involves the recruitment of MLL1 and MLL2 H3K4 histone methyltransferase complexes.Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells.
P2860
Q24537610-473CF596-269F-4ADB-BBDB-C8734753AC73Q33706844-530768EF-62B5-4501-926E-1F2868B11F2BQ35900991-8FE881D2-99FA-4F1F-8447-0C4CB4B7DC24Q37146086-3F6D7D66-9AC3-4B15-8619-7A8FA6D2FCE8Q38162229-758FBF7F-B0FB-4167-AF7E-B5D179AF6113Q42803133-0D48B2FC-B5B1-4903-A415-8AC673AC09A7Q44611183-A2A26703-2867-4E21-808A-ADCE21D53BDD
P2860
Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein.
description
2000 nî lūn-bûn
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name
Mutant envelope residues confe ...... nces of the v-Rel oncoprotein.
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type
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Mutant envelope residues confe ...... nces of the v-Rel oncoprotein.
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Mutant envelope residues confe ...... nces of the v-Rel oncoprotein.
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Mutant envelope residues confe ...... nces of the v-Rel oncoprotein.
@en
P2093
Gilmore TD
Harkness DD
Kazandjian D
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P356
10.1038/SJ.ONC.1203376
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2000-02-01T00:00:00Z
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P6179
1027197138