Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells.
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Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.Novel functional properties of Ca(2+) channel beta subunits revealed by their expression in adult rat heart cellsGene and cell therapies for the failing heart to prevent sudden arrhythmic deathCa(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequencesDirect interaction of CaVβ with actin up-regulates L-type calcium currents in HL-1 cardiomyocytesThe neuronal beta 4 subunit increases the unitary conductance of L-type voltage-gated calcium channels in PC12 cellsCloning of a functional splice variant of L-type calcium channel beta 2 subunit from rat heartThe ß subunit of voltage-gated Ca2+ channelsA CaVbeta SH3/guanylate kinase domain interaction regulates multiple properties of voltage-gated Ca2+ channels.Properties of voltage-gated Ca(2+) channels in rabbit ventricular myocytes expressing Ca(2+) channel alpha(1E) cDNA.Ser(1901) of alpha(1C) subunit is required for the PKA-mediated enhancement of L-type Ca(2+) channel currents but not for the negative shift of activation.Increased expression of the auxiliary beta(2)-subunit of ventricular L-type Ca(2)+ channels leads to single-channel activity characteristic of heart failureEnhanced basal contractility but reduced excitation-contraction coupling efficiency and beta-adrenergic reserve of hearts with increased Cav1.2 activity.The L-type calcium channel in the heart: the beat goes onTruncation of the carboxyl terminus of the dihydropyridine receptor beta1a subunit promotes Ca2+ dependent excitation-contraction coupling in skeletal myotubes.Ca2+ current and charge movements in skeletal myotubes promoted by the beta-subunit of the dihydropyridine receptor in the absence of ryanodine receptor type 1.Ca2+-dependent excitation-contraction coupling triggered by the heterologous cardiac/brain DHPR beta2a-subunit in skeletal myotubesVoltage-gated rearrangements associated with differential beta-subunit modulation of the L-type Ca(2+) channel inactivationOligomerization of Cavbeta subunits is an essential correlate of Ca2+ channel activity.Engineered calmodulins reveal the unexpected eminence of Ca2+ channel inactivation in controlling heart excitation.Moderate calcium channel dysfunction in adult mice with inducible cardiomyocyte-specific excision of the cacnb2 gene.Decreased myocardial injury and improved contractility after administration of a peptide derived against the alpha-interacting domain of the L-type calcium channelCalcium and arrhythmogenesis.Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β1a Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal MyotubesRegulation of maximal open probability is a separable function of Ca(v)beta subunit in L-type Ca2+ channel, dependent on NH2 terminus of alpha1C (Ca(v)1.2alpha).Reverse engineering the L-type Ca2+ channel alpha1c subunit in adult cardiac myocytes using novel adenoviral vectorsRegulation of cardiac CACNB2 by microRNA-499: Potential role in atrial fibrillation.Structure and function of the β subunit of voltage-gated Ca²⁺ channels.Proteolytic cleavage of the hydrophobic domain in the CaVα2δ1 subunit improves assembly and activity of cardiac CaV1.2 channels.Plasma membrane expression of T-type calcium channel alpha(1) subunits is modulated by high voltage-activated auxiliary subunits.Cardiac L-type calcium channel beta-subunits expressed in human heart have differential effects on single channel characteristics.Functional interaction of auxiliary subunits and synaptic proteins with Ca(v)1.3 may impart hair cell Ca2+ current properties.Chronic verapamil treatment remodels ICa,L in mouse ventricle.Ahnak1 modulates L-type Ca(2+) channel inactivation of rodent cardiomyocytes.The interaction between the I-II loop and the III-IV loop of Cav2.1 contributes to voltage-dependent inactivation in a beta -dependent manner.The beta1a subunit regulates the functional properties of adult frog and mouse L-type Ca2+ channels of skeletal muscle.
P2860
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P2860
Ca(2+) channel modulation by recombinant auxiliary beta subunits expressed in young adult heart cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Ca(2+) channel modulation by r ...... ed in young adult heart cells.
@en
type
label
Ca(2+) channel modulation by r ...... ed in young adult heart cells.
@en
prefLabel
Ca(2+) channel modulation by r ...... ed in young adult heart cells.
@en
P2093
P356
P1433
P1476
Ca(2+) channel modulation by r ...... ed in young adult heart cells.
@en
P2093
Colecraft HM
DeMaria CD
Peterson BZ
P304
P356
10.1161/01.RES.86.2.175
P577
2000-02-01T00:00:00Z