Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells.
about
Microtubule plus-ends reveal essential links between intracellular polarization and localized modulation of endocytosis during division-plane establishment in plant cells.Centrosome-associated regulators of the G(2)/M checkpoint as targets for cancer therapyInvolvement of the telomeric protein Pin2/TRF1 in the regulation of the mitotic spindleIdentification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cellsErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEFHuman scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coliInteraction of CDK5RAP2 with EB1 to track growing microtubule tips and to regulate microtubule dynamicsAttenuated APC alleles produce functional protein from internal translation initiation.APC and EB1 function together in mitosis to regulate spindle dynamics and chromosome alignment.Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosomeEB1 targets to kinetochores with attached, polymerizing microtubulesEB1 proteins regulate microtubule dynamics, cell polarity, and chromosome stabilityThe Rho-mDia1 pathway regulates cell polarity and focal adhesion turnover in migrating cells through mobilizing Apc and c-SrcCytoplasmic linker proteins promote microtubule rescue in vivoSpatial regulation of CLASP affinity for microtubules by Rac1 and GSK3beta in migrating epithelial cellsIntracellular shuttling of a Drosophila APC tumour suppressor homologExamination of actin and microtubule dependent APC localisations in living mammalian cells.Targeting and transport: how microtubules control focal adhesion dynamicsCoordination of cell polarity during Xenopus gastrulationEB1 is required for spindle symmetry in mammalian mitosisGroup IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.Structure of the Human Discs Large 1 PDZ2– Adenomatous Polyposis Coli Cytoskeletal Polarity Complex: Insight into Peptide Engagement and PDZ ClusteringPolyploids require Bik1 for kinetochore-microtubule attachment.Identification of a link between the tumour suppressor APC and the kinesin superfamilyActin-dependent membrane association of the APC tumour suppressor in polarized mammalian epithelial cellsMembrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-cateninMitogen-activated protein kinase (MAPK/ERK) regulates adenomatous polyposis coli during growth-factor-induced cell extensionAdenomatous polyposis coli on microtubule plus ends in cell extensions can promote microtubule net growth with or without EB1.Insulin signaling regulates a functional interaction between adenomatous polyposis coli and cytoplasmic dynein.Conserved microtubule-actin interactions in cell movement and morphogenesisAdenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion.Genome-wide screen reveals APC-associated RNAs enriched in cell protrusionsCharacterization of a 60S complex of the adenomatous polyposis coli tumor suppressor protein.Accumulation of cytoplasmic dynein and dynactin at microtubule plus ends in Aspergillus nidulans is kinesin dependentThe adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.Rocket launcher mechanism of collaborative actin assembly defined by single-molecule imaging.Multiparametric analysis of CLASP-interacting protein functions during interphase microtubule dynamics.Reaction-diffusion systems in intracellular molecular transport and controlMicrotubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.
P2860
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P2860
Adenomatous polyposis coli (APC) protein moves along microtubules and concentrates at their growing ends in epithelial cells.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh
2000年學術文章
@zh-hant
name
Adenomatous polyposis coli (AP ...... wing ends in epithelial cells.
@en
type
label
Adenomatous polyposis coli (AP ...... wing ends in epithelial cells.
@en
prefLabel
Adenomatous polyposis coli (AP ...... wing ends in epithelial cells.
@en
P2093
P2860
P356
P1476
Adenomatous polyposis coli (AP ...... wing ends in epithelial cells.
@en
P2093
Y Mimori-Kiyosue
P2860
P304
P356
10.1083/JCB.148.3.505
P407
P577
2000-02-01T00:00:00Z