Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.
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Negative Regulation of BRCA1 Gene Expression by HMGA1 Proteins Accounts for the Reduced BRCA1 Protein Levels in Sporadic Breast CarcinomaHigh mobility group I (Y) proteins bind HIPK2, a serine-threonine kinase protein which inhibits cell growth.P27(Kip1), regulated by glycogen synthase kinase-3β, results in HMBA-induced differentiation of human gastric cancer cells.Complex regulation of the cyclin-dependent kinase inhibitor p27kip1 in thyroid cancer cells by the PI3K/AKT pathway: regulation of p27kip1 expression and localizationFEZ1/LZTS1 is down-regulated in high-grade bladder cancer, and its restoration suppresses tumorigenicity in transitional cell carcinoma cells.Expression of D-type cyclins in colon cancer and in cell lines from colon carcinomas.Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin.Homeodomain-interacting protein kinase-2 stabilizes p27(kip1) by its phosphorylation at serine 10 and contributes to cell motility.ADAM23 knockdown promotes neuronal differentiation of P19 embryonal carcinoma cells by up-regulating P27KIP1 expression.PKC-dependent phosphorylation of p27 at T198 contributes to p27 stabilization and cell cycle arrest.Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.Glial cell line-derived neurotrophic factor induces proliferative inhibition of NT2/D1 cells through RET-mediated up-regulation of the cyclin-dependent kinase inhibitor p27(kip1).P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells.Overexpressed cyclin D3 contributes to retaining the growth inhibitor p27 in the cytoplasm of thyroid tumor cells.Bcl2 enhances induced hematopoietic differentiation of murine embryonic stem cells.Immunohistochemical localization of mdm-2, p27Kip1 and bcl-2 in Warthin's tumor of the parotid gland.
P2860
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P2860
Key role of the cyclin-dependent kinase inhibitor p27kip1 for embryonal carcinoma cell survival and differentiation.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Key role of the cyclin-depende ...... survival and differentiation.
@en
type
label
Key role of the cyclin-depende ...... survival and differentiation.
@en
prefLabel
Key role of the cyclin-depende ...... survival and differentiation.
@en
P2093
P2860
P356
P1433
P1476
Key role of the cyclin-depende ...... l survival and differentiation
@en
P2093
C Sandomenico
G Baldassarre
G Viglietto
M V Barone
P2860
P2888
P304
P356
10.1038/SJ.ONC.1203031
P407
P577
1999-11-01T00:00:00Z
P5875
P6179
1041539287