Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway.
about
Molecular cloning and characterization of DEFCAP-L and -S, two isoforms of a novel member of the mammalian Ced-4 family of apoptosis proteinsKep1 interacts genetically with dredd/caspase-8, and kep1 mutants alter the balance of dredd isoformsMultiple apoptotic caspase cascades are required in nonapoptotic roles for Drosophila spermatid individualizationInhibitor of apoptosis (IAP) proteins-modulators of cell death and inflammationMolecular mechanism of Reaper-Grim-Hid-mediated suppression of DIAP1-dependent Dronc ubiquitinationStructure of the Drosophila Apoptosome at 6.9 Å ResolutionA novel enhancer of the Apaf1 apoptosome involved in cytochrome c-dependent caspase activation and apoptosisThe Toll pathway is important for an antiviral response in DrosophilaMutations in the Drosophila dTAK1 gene reveal a conserved function for MAPKKKs in the control of rel/NF-kappaB-dependent innate immune responsesThe Nod-like receptor (NLR) family: a tale of similarities and differencesConcentration-dependent, size-independent toxicity of citrate capped AuNPs in Drosophila melanogasterLocal initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo.A collective form of cell death requires homeodomain interacting protein kinase.The role of the RING-finger protein Elfless in Drosophila spermatogenesis and apoptosisGenome-wide silencing in Drosophila captures conserved apoptotic effectors.Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).Cell death regulation in Drosophila: conservation of mechanism and unique insights.Caspase-dependent inactivation of proteasome function during programmed cell death in Drosophila and man.A ubiquitin ligase complex regulates caspase activation during sperm differentiation in Drosophila.Activation mechanism and substrate specificity of the Drosophila initiator caspase DRONC.Cleavage of Armadillo/beta-catenin by the caspase DrICE in Drosophila apoptotic epithelial cellsThe role of ubiquitylation for the control of cell death in DrosophilaDimorphic ovary differentiation in honeybee (Apis mellifera) larvae involves caste-specific expression of homologs of ark and buffy cell death genes.The Drosophila caspase Dredd is required to resist gram-negative bacterial infection.The Jekyll and Hyde functions of caspases.Regulation and execution of apoptosis during Drosophila development.Proteases for cell suicide: functions and regulation of caspases.The caspase-8 homolog Dredd cleaves Imd and Relish but is not inhibited by p35The Drosophila casein kinase Iepsilon/delta Discs overgrown promotes cell survival via activation of DIAP1 expression.The molecular archaeology of a mitochondrial death effector: AIF in Drosophila.Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation.Genetic regulation of programmed cell death in Drosophila.GH3, a novel proapoptotic domain in Drosophila Grim, promotes a mitochondrial death pathwayCharacterization of three alternatively spliced isoforms of the Rel/NF-kappa B transcription factor Relish from the mosquito Aedes aegypti.Formation of apoptosome is initiated by cytochrome c-induced dATP hydrolysis and subsequent nucleotide exchange on Apaf-1.Molecular mechanisms of cell death and phagocytosis in Drosophila.Guardian ancestry: fly p53 and damage-inducible apoptosis.The fly caspases.Steroid regulation of programmed cell death during Drosophila development.
P2860
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P2860
Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Dark is a Drosophila homologue ...... arily conserved death pathway.
@en
type
label
Dark is a Drosophila homologue ...... arily conserved death pathway.
@en
prefLabel
Dark is a Drosophila homologue ...... arily conserved death pathway.
@en
P2093
P356
P1433
P1476
Dark is a Drosophila homologue ...... arily conserved death pathway.
@en
P2093
P2888
P304
P356
10.1038/12984
P577
1999-09-01T00:00:00Z