Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?
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Comparative developmental neurotoxicity of organophosphate insecticides: effects on brain development are separable from systemic toxicityDevelopmental neurotoxicity of perfluorinated chemicals modeled in vitroDevelopmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling.Developmental effects of chlorpyrifos extend beyond neurotoxicity: critical periods for immediate and delayed-onset effects on cardiac and hepatic cell signaling.Critical periods for chlorpyrifos-induced developmental neurotoxicity: alterations in adenylyl cyclase signaling in adult rat brain regions after gestational or neonatal exposureAn invertebrate model of the developmental neurotoxicity of insecticides: effects of chlorpyrifos and dieldrin in sea urchin embryos and larvaeDevelopmental neurotoxicity of chlorpyrifos modeled in vitro: comparative effects of metabolites and other cholinesterase inhibitors on DNA synthesis in PC12 and C6 cells.Fetal chlorpyrifos exposure: adverse effects on brain cell development and cholinergic biomarkers emerge postnatally and continue into adolescence and adulthood.Developmental neurotoxicity elicited by gestational exposure to chlorpyrifos: when is adenylyl cyclase a target?Incorporating Low-dose Epidemiology Data in a Chlorpyrifos Risk AssessmentChlorpyrifos and chlorpyrifos-oxon inhibit axonal growth by interfering with the morphogenic activity of acetylcholinesteraseDevelopmental neurotoxicants target neurodifferentiation into the serotonin phenotype: Chlorpyrifos, diazinon, dieldrin and divalent nickelChlorpyrifos-oxon disrupts zebrafish axonal growth and motor behaviorAssociations of maternal organophosphate pesticide exposure and PON1 activity with birth outcomes in SAWASDEE birth cohort, ThailandScreening for developmental neurotoxicity using PC12 cells: comparisons of organophosphates with a carbamate, an organochlorine, and divalent nickelExposure to organophosphates reduces the expression of neurotrophic factors in neonatal rat brain regions: similarities and differences in the effects of chlorpyrifos and diazinon on the fibroblast growth factor superfamilyEffects of tobacco smoke on PC12 cell neurodifferentiation are distinct from those of nicotine or benzo[a]pyrene.Zebrafish provide a sensitive model of persisting neurobehavioral effects of developmental chlorpyrifos exposure: comparison with nicotine and pilocarpine effects and relationship to dopamine deficitsDiverse neurotoxicants converge on gene expression for neuropeptides and their receptors in an in vitro model of neurodifferentiation: effects of chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.Dose-related gene expression changes in forebrain following acute, low-level chlorpyrifos exposure in neonatal rats.Chlorpyrifos affects phenotypic outcomes in a model of mammalian neurodevelopment: critical stages targeting differentiation in PC12 cells.Nonenzymatic functions of acetylcholinesterase splice variants in the developmental neurotoxicity of organophosphates: chlorpyrifos, chlorpyrifos oxon, and diazinon.Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems.Ameliorating the developmental neurotoxicity of chlorpyrifos: a mechanisms-based approach in PC12 cellsChlorpyrifos developmental neurotoxicity: interaction with glucocorticoids in PC12 cellsNeonatal exposure to low doses of diazinon: long-term effects on neural cell development and acetylcholine systemsTargeting of neurotrophic factors, their receptors, and signaling pathways in the developmental neurotoxicity of organophosphates in vivo and in vitro.Supraphysiological doses of performance enhancing anabolic-androgenic steroids exert direct toxic effects on neuron-like cells.Adverse benzo[a]pyrene effects on neurodifferentiation are altered by other neurotoxicant coexposures: interactions with dexamethasone, chlorpyrifos, or nicotine in PC12 cellsTranscriptional profiles reveal similarities and differences in the effects of developmental neurotoxicants on differentiation into neurotransmitter phenotypes in PC12 cells.Developmental neurotoxic effects of chlorpyrifos on acetylcholine and serotonin pathways in an avian model.Ultraviolet photolysis of chlorpyrifos: developmental neurotoxicity modeled in PC12 cells.Oxidative and excitatory mechanisms of developmental neurotoxicity: transcriptional profiles for chlorpyrifos, diazinon, dieldrin, and divalent nickel in PC12 cellsHypothesis-based weight-of-evidence evaluation of the neurodevelopmental effects of chlorpyrifos.The neuronal cytoskeleton as a potential target in the developmental neurotoxicity of organophosphorothionate insecticides.Diazoxon disrupts the expression and distribution of βIII-tubulin and MAP 1B in differentiating N2a cells.Transcriptional profiles for glutamate transporters reveal differences between organophosphates but similarities with unrelated neurotoxicantsOrganophosphate exposure during a critical developmental stage reprograms adenylyl cyclase signaling in PC12 cells.Protein kinase C is a target for diverse developmental neurotoxicants: transcriptional responses to chlorpyrifos, diazinon, dieldrin and divalent nickel in PC12 cells.Neurofilament 200 as an indicator of differences between mipafox and paraoxon sensitivity in Sy5Y neuroblastoma cells.
P2860
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P2860
Neuronal differentiation in PC12 cells is inhibited by chlorpyrifos and its metabolites: is acetylcholinesterase inhibition the site of action?
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Neuronal differentiation in PC ...... inhibition the site of action?
@en
type
label
Neuronal differentiation in PC ...... inhibition the site of action?
@en
prefLabel
Neuronal differentiation in PC ...... inhibition the site of action?
@en
P356
P1476
Neuronal differentiation in PC ...... inhibition the site of action?
@en
P2093
P304
P356
10.1006/TAAP.1999.8767
P577
1999-11-01T00:00:00Z