A selection system for functional internal ribosome entry site (IRES) elements: analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES.
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NMD resulting from encephalomyocarditis virus IRES-directed translation initiation seems to be restricted to CBP80/20-bound mRNAUpf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decayHuman insulin-like growth factor II leader 2 mediates internal initiation of translationStructural organization of a viral IRES depends on the integrity of the GNRA motif.Biological function of Foot-and-mouth disease virus non-structural proteins and non-coding elementsIn vivo and in vitro identification of structural and sequence elements of the human parechovirus 5' untranslated region required for internal initiationMonocistronic mRNAs containing defective hepatitis C virus-like picornavirus internal ribosome entry site elements in their 5' untranslated regions are efficiently translated in cells by a cap-dependent mechanismInsights into the Biology of IRES Elements through Riboproteomic ApproachesDistinctive properties of the 5'-untranslated region of human hsp70 mRNANovel fluorescence-based screen to identify small synthetic internal ribosome entry site elementsNMR studies of the structure and Mg2+ binding properties of a conserved RNA motif of EMCV picornavirus IRES elementMg2+ modulation of EMCV IRES key activity fragment equilibria and r(G*C) base-pair kinetics.An internal ribosome entry site directs translation of the 3'-gene from Pelargonium flower break virus genomic RNA: implications for infectivity.The 5' untranslated region of Rhopalosiphum padi virus contains an internal ribosome entry site which functions efficiently in mammalian, plant, and insect translation systems.Common conformational changes induced in type 2 picornavirus IRESs by cognate trans-acting factors.A distinct class of internal ribosomal entry site in members of the Kobuvirus and proposed Salivirus and Paraturdivirus genera of the Picornaviridae.Premature Termination Codons Are Recognized in the Nucleus in A Reading-Frame Dependent MannerCandidate RNA structures for domain 3 of the foot-and-mouth-disease virus internal ribosome entry site.PCBP2 enables the cadicivirus IRES to exploit the function of a conserved GRNA tetraloop to enhance ribosomal initiation complex formation.Using RNA inverse folding to identify IRES-like structural subdomains.Role of RNA structure motifs in IRES-dependent translation initiation of the coxsackievirus B3: new insights for developing live-attenuated strains for vaccines and gene therapy.Conserved nucleotides within the J domain of the encephalomyocarditis virus internal ribosome entry site are required for activity and for interaction with eIF4G.Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation.A researcher's guide to the galaxy of IRESs.The mechanism of translation initiation on Aichivirus RNA mediated by a novel type of picornavirus IRES.Tailoring the switch from IRES-dependent to 5'-end-dependent translation with the RNase P ribozyme.Comparative genetics. Systematic discovery of cap-independent translation sequences in human and viral genomes.Internal ribosome entry sequence-mediated translation initiation triggers nonsense-mediated decay.Construction and characterization of an infectious cDNA clone of encephalomyocarditis virus from pigs in China.A single internal ribosome entry site containing a G quartet RNA structure drives fibroblast growth factor 2 gene expression at four alternative translation initiation codons.Characterization of a cyanobacterial RNase P ribozyme recognition motif in the IRES of foot-and-mouth disease virus reveals a unique structural element.A cross-kingdom internal ribosome entry site reveals a simplified mode of internal ribosome entry.NMR elucidation of the role of Mg2+ in the structure and stability of the conserved RNA motifs of the EMCV IRES element.Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs.Analysis of a Charcot-Marie-Tooth disease mutation reveals an essential internal ribosome entry site element in the connexin-32 gene.Raman and Raman optical activity (ROA) analysis of RNA structural motifs in Domain I of the EMCV IRES.Cross-talk between orientation-dependent recognition determinants of a complex control RNA element, the enterovirus oriR.Evidence of reciprocal tertiary interactions between conserved motifs involved in organizing RNA structure essential for internal initiation of translation.In silico analysis of IRES RNAs of foot-and-mouth disease virus and related picornaviruses.Evolutionary conserved motifs constrain the RNA structure organization of picornavirus IRES.
P2860
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P2860
A selection system for functional internal ribosome entry site (IRES) elements: analysis of the requirement for a conserved GNRA tetraloop in the encephalomyocarditis virus IRES.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A selection system for functio ...... cephalomyocarditis virus IRES.
@en
type
label
A selection system for functio ...... cephalomyocarditis virus IRES.
@en
prefLabel
A selection system for functio ...... cephalomyocarditis virus IRES.
@en
P2860
P1433
P1476
A selection system for functio ...... cephalomyocarditis virus IRES.
@en
P2093
Robertson ME
Seamons RA
P2860
P304
P356
10.1017/S1355838299990301
P407
P577
1999-09-01T00:00:00Z