A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
about
PAX2 suppresses apoptosis in renal collecting duct cellsExpression of the Bcl-3 proto-oncogene suppresses p53 activationFinding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chipsPharmacological manipulation of cell death: clinical applications in sight?Regulation of autophagy by cytoplasmic p53Finding the needle in the haystack: why high-throughput screening is good for your health.The p53-inhibitor pifithrin-alpha inhibits firefly luciferase activity in vivo and in vitroGenetic Stabilization by p53 Involves Growth Regulatory and Repair PathwaysProteomic identification of heat shock protein 90 as a candidate target for p53 mutation reactivation by PRIMA-1 in breast cancer cellsMolecular signatures associated with ZIKV exposure in human cortical neural progenitorsPhytochemicals and Biogenic Metallic Nanoparticles as Anticancer AgentsEmerging Treatment Paradigms in Radiation OncologyDisruptive chemicals, senescence and immortalityEndothelial perturbations and therapeutic strategies in normal tissue radiation damageHsp70 May Be a Molecular Regulator of Schistosome Host InvasionIntracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeletonA Small Molecule Binding to the Coactivator CREB-Binding Protein Blocks Apoptosis in CardiomyocytesTherapeutic targeting of the MYC signal by inhibition of histone chaperone FACT in neuroblastoma.Emerging Non-Canonical Functions and Regulation by p53: p53 and StemnessThe Roles of Syncytin-Like Proteins in Ruminant PlacentationDrugging the cancer kinome: progress and challenges in developing personalized molecular cancer therapeuticsThe synthetic purine reversine selectively induces cell death of cancer cellsSodium butyrate induces P53-independent, Fas-mediated apoptosis in MCF-7 human breast cancer cellsActivation and activities of the p53 tumour suppressor proteinPotential therapeutic approaches for modulating expression and accumulation of defective lamin A in laminopathies and age-related diseasesp53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening systemHuman monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistantIdentification of BC005512 as a DNA damage responsive murine endogenous retrovirus of GLN family involved in cell growth regulationTransient transfection of a wild-type p53 gene triggers resveratrol-induced apoptosis in cancer cellsBortezomib is cytotoxic to the human growth plate and permanently impairs bone growth in young miceInduction of p53-dependent p21 limits proliferative activity of rat hepatocytes in the presence of hepatocyte growth factorNSC666715 and Its Analogs Inhibit Strand-Displacement Activity of DNA Polymerase β and Potentiate Temozolomide-Induced DNA Damage, Senescence and Apoptosis in Colorectal Cancer CellsThe Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human PrimatesNitric Oxide Down-Regulates Topoisomerase I and Induces Camptothecin Resistance in Human Breast MCF-7 Tumor CellsInternal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic CellsPotential role of PUMA in delayed death of hippocampal CA1 neurons after transient global cerebral ischemiaInflammatory cells regulate p53 and caspases in acute pancreatitisMultiple actions of pifithrin-alpha on doxorubicin-induced apoptosis in rat myoblastic H9c2 cellsActivation of the p53-p21(Cip1) pathway is required for CDK2 activation and S-phase entry in primary rat hepatocytesAnalysis of p53 and NF-κB signaling in modulating the cardiomyocyte fate during hypertrophy
P2860
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P2860
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
@en
type
label
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
@en
prefLabel
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
@en
P2093
P1433
P1476
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapy.
@en
P2093
A V Gudkov
E A Komarova
K Christov-Tselkov
M V Chernov
P G Komarov
R V Kondratov
P304
P356
10.1126/SCIENCE.285.5434.1733
P407
P577
1999-09-01T00:00:00Z