Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds.

Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds.

Item
http://www.wikidata.org/entity/Q40930792
Genetic toxicology in the 21st century: reflections and future directions.Toward a greater appreciation of noncovalent chemical/DNA interactions: application of biological and computational approaches.Emerging approaches in predictive toxicology.In vitro approaches to develop weight of evidence (WoE) and mode of action (MoA) discussions with positive in vitro genotoxicity results.Possible structural and functional determinants contributing to the clastogenicity of pharmaceuticals.Follow-up actions from positive results of in vitro genetic toxicity testing.Potentiation of the mutagenicity and recombinagenicity of bleomycin in yeast by unconventional intercalating agents.Lovastatin enhances the genotoxicity of doxorubicin in Chinese hamster V79 cells via noncovalent DNA binding.Evaluation of DNA intercalation potential of pharmaceuticals and other chemicals by cell-based and three-dimensional computational approaches.Evidence for and role of the dimethylamino group in tamoxifen DNA intercalation in intact Chinese hamster V79 cells.An update on the genotoxicity and carcinogenicity of marketed pharmaceuticals with reference to in silico predictivity.The genotoxicity of DNA intercalating drug 8-methoxy pyrimido [4',5':4,5]thieno(2,3-b)quinoline-4(3H)-one.Assessment of the sensitivity of the computational programs DEREK, TOPKAT, and MCASE in the prediction of the genotoxicity of pharmaceutical molecules.
P2860

Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds.

Item
http://www.wikidata.org/entity/Q40930792
description
1999 nî lūn-bûn
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1999年の論文
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1999年論文
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1999年論文
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1999年論文
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1999年論文
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1999年論文
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1999年论文
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1999年论文
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1999年论文
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name
Enhancement of bleomycin-induc ...... ovalent DNA-binding compounds.
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type
label
Enhancement of bleomycin-induc ...... ovalent DNA-binding compounds.
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Enhancement of bleomycin-induc ...... ovalent DNA-binding compounds.
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P1476
P2093
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Enhancement of bleomycin-induc ...... ovalent DNA-binding compounds.
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P2093
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P356
10.1016/S1383-5718(99)00080-7
P407
P433
P478
P577
P698