Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene.
about
BRCA1 and FOXA1 proteins coregulate the expression of the cell cycle-dependent kinase inhibitor p27(Kip1)Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cellsEpigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancersHypoxia actively represses transcription by inducing negative cofactor 2 (Dr1/DrAP1) and blocking preinitiation complex assemblyA direct intersection between p53 and transforming growth factor beta pathways targets chromatin modification and transcription repression of the alpha-fetoprotein geneChromatin-bound p53 anchors activated Smads and the mSin3A corepressor to confer transforming-growth-factor-beta-mediated transcription repressionTranscription factor interactions and chromatin modifications associated with p53-mediated, developmental repression of the alpha-fetoprotein gene.Reprogramming transcription by distinct classes of enhancers functionally defined by eRNAA cell-type-specific transcriptional network required for estrogen regulation of cyclin D1 and cell cycle progression in breast cancer.Zhx2 and Zbtb20: novel regulators of postnatal alpha-fetoprotein repression and their potential role in gene reactivation during liver cancer.Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies.Global analysis of in vivo Foxa2-binding sites in mouse adult liver using massively parallel sequencingCharacterization of cis elements of the probasin promoter necessary for prostate-specific gene expression.Alpha-fetoprotein: from a diagnostic biomarker to a key role in female fertilityThe Fox genes in the liver: from organogenesis to functional integration.Structure and functions of powerful transactivators: VP16, MyoD and FoxA.Transcriptional networks in liver and intestinal development.Inhibition of p53 expression modifies the specificity of chromatin binding by the androgen receptor.Overexpression of caspase-3 in hepatocellular carcinomas.Variant forms of alpha-fetoprotein transcripts expressed in human hematopoietic progenitors. Implications for their developmental potential towards endoderm.Serum hepatitis B surface antigen correlates with tissue covalently closed circular DNA in patients with hepatitis B-associated hepatocellular carcinoma.The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (FOXA).Assessing prognostic significance of preoperative alpha-fetoprotein in hepatitis B-associated hepatocellular carcinoma: normal is not the new normal.p53 targets chromatin structure alteration to repress alpha-fetoprotein gene expression.Sequence and spacing of TATA box elements are critical for accurate initiation from the beta-phaseolin promoter.
P2860
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P2860
Hepatocyte nuclear factor 3 relieves chromatin-mediated repression of the alpha-fetoprotein gene.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Hepatocyte nuclear factor 3 re ...... of the alpha-fetoprotein gene.
@en
type
label
Hepatocyte nuclear factor 3 re ...... of the alpha-fetoprotein gene.
@en
prefLabel
Hepatocyte nuclear factor 3 re ...... of the alpha-fetoprotein gene.
@en
P2093
P2860
P356
P1476
Hepatocyte nuclear factor 3 re ...... of the alpha-fetoprotein gene.
@en
P2093
P2860
P304
25113-25120
P356
10.1074/JBC.274.35.25113
P407
P577
1999-08-01T00:00:00Z