Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.
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Disposition and metabolism of the flavonoid chrysin in normal volunteersIn vitro digestion and lactase treatment influence uptake of quercetin and quercetin glucoside by the Caco-2 cell monolayerEpicatechin and its in vivo metabolite, 3'-O-methyl epicatechin, protect human fibroblasts from oxidative-stress-induced cell death involving caspase-3 activationRole of multidrug resistance protein 2 (MRP2) in glutathione-bimane efflux from Caco-2 and rat renal proximal tubule cellsModulation of cytochrome P450 metabolism and transport across intestinal epithelial barrier by ginger biophenolicsSecretory transport of p-aminohippuric acid across intestinal epithelial cells in Caco-2 cells and isolated intestinal tissue.Plasma, tissue and urinary levels of aloin in rats after the administration of pure aloin.Apigenin and its impact on gastrointestinal cancers.Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo.Glutathione conjugates and their synthetic derivatives as inhibitors of glutathione-dependent enzymes involved in cancer and drug resistance.In vitro studies of intestinal permeability and hepatic and intestinal metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus L.).ABC of oral bioavailability: transporters as gatekeepers in the gut.Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione.Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis.Methoxylated flavones, a superior cancer chemopreventive flavonoid subclass?SULT1A3-mediated regiospecific 7-O-sulfation of flavonoids in Caco-2 cells can be explained by the relevant molecular docking studies.First-pass metabolism via UDP-glucuronosyltransferase: a barrier to oral bioavailability of phenolics.Systematic studies of sulfation and glucuronidation of 12 flavonoids in the mouse liver S9 fraction reveal both unique and shared positional preferences.Caco-2 cell permeability assays to measure drug absorption.Metabolism of ATP-binding cassette drug transporter inhibitors: complicating factor for multidrug resistance.Improving metabolic stability of cancer chemoprotective polyphenols.Pharmacokinetic Interaction of Chrysin with Caffeine in Rats.MRP isoforms and BCRP mediate sulfate conjugate efflux out of BeWo cells.UDP-glucuronosyltransferases (UGTs): from purification of Ah-receptor-inducible UGT1A6 to coordinate regulation of subsets of CYPs, UGTs, and ABC transporters by nuclear receptors.Hepatic metabolism and disposition of baicalein via the coupling of conjugation enzymes and transporters-in vitro and in vivo evidences.Modifications of dietary flavonoids towards improved bioactivity: An update on structure-activity relationship.Glucose induces intestinal human UDP-glucuronosyltransferase (UGT) 1A1 to prevent neonatal hyperbilirubinemia.Polyphenols Beyond Barriers: A Glimpse into the Brain.Anti-proliferative effects of quercetin and catechin metabolites.Plant polyphenols and multidrug resistance: effects of dietary flavonoids on drug transporters in Caco-2 and MDCKII-MDR1 cell transport models.Transport of thalidomide by the human intestinal caco-2 monolayers.MK571 inhibits phase-2 conjugation of flavonols by Caco-2/TC7 cells, but does not specifically inhibit their apical efflux.Resveratrol transport and metabolism by human intestinal Caco-2 cells.Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4.Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells.Bioaccessibility, Intestinal Permeability and Plasma Stability of Isorhamnetin Glycosides from Opuntia ficus-indica (L.).Absorption, Conjugation and Efflux of the Flavonoids, Kaempferol and Galangin, Using the Intestinal CACO-2/TC7 Cell Model.The effect of rifampin treatment on intestinal expression of human MRP transporters.Comparison of In Vitro Assays in Selecting Radiotracers for In Vivo P-Glycoprotein PET ImagingDisposition of naringenin via glucuronidation pathway is affected by compensating efflux transporters of hydrophilic glucuronides.
P2860
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P2860
Transport of the flavonoid chrysin and its conjugated metabolites by the human intestinal cell line Caco-2.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Transport of the flavonoid chr ...... n intestinal cell line Caco-2.
@en
type
label
Transport of the flavonoid chr ...... n intestinal cell line Caco-2.
@en
prefLabel
Transport of the flavonoid chr ...... n intestinal cell line Caco-2.
@en
P2093
P1476
Transport of the flavonoid chr ...... n intestinal cell line Caco-2.
@en
P2093
P304
P356
10.1016/S0006-2952(99)00133-1
P407
P577
1999-08-01T00:00:00Z