A human prostatic stromal myofibroblast cell line WPMY-1: a model for stromal-epithelial interactions in prostatic neoplasia.
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P1343
Differential expression of protease-activated receptors-1 and -2 in stromal fibroblasts of normal, benign, and malignant human tissuesGenomewide analyses define different modes of transcriptional regulation by peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)Repurposed drug screen identifies cardiac glycosides as inhibitors of TGF-β-induced cancer-associated fibroblast differentiationIsolation and characterization of an immortalized mouse urogenital sinus mesenchyme cell lineEffects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cellsTranscriptional activation by NFκB increases perlecan/HSPG2 expression in the desmoplastic prostate tumor microenvironmentElevated GnRH receptor expression plus GnRH agonist treatment inhibits the growth of a subset of papillomavirus 18-immortalized human prostate cells.Myofibroblasts: paracrine cells important in health and diseaseCultured stromal cells: an in vitro model of prostatic mesenchymal biology.Kava components down-regulate expression of AR and AR splice variants and reduce growth in patient-derived prostate cancer xenografts in miceThe polyphenols (-)-epigallocatechin-3-gallate and luteolin synergistically inhibit TGF-β-induced myofibroblast phenotypes through RhoA and ERK inhibitionProstate stromal and urogenital sinus mesenchymal cell lines for investigations of stromal-epithelial interactions.In vitro and in vivo model systems used in prostate cancer research.High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S)Loss of stromal androgen receptor leads to suppressed prostate tumourigenesis via modulation of pro-inflammatory cytokines/chemokinesAndrogen receptor is a tumor suppressor and proliferator in prostate cancer.Targeting the stromal androgen receptor in primary prostate tumors at earlier stages.Androgen receptor (AR) suppresses normal human prostate epithelial cell proliferation via AR/β-catenin/TCF-4 complex inhibition of c-MYC transcription.The diverse and contrasting effects of using human prostate cancer cell lines to study androgen receptor roles in prostate cancer.Targeting stromal androgen receptor suppresses prolactin-driven benign prostatic hyperplasia (BPH).Reduced Contractility and Motility of Prostatic Cancer-Associated Fibroblasts after Inhibition of Heat Shock Protein 90Stromal Androgen Receptor in Prostate Cancer Development and ProgressionLoss of caveolin-1 in prostate cancer stroma correlates with reduced relapse-free survival and is functionally relevant to tumour progression.Differential androgen receptor signals in different cells explain why androgen-deprivation therapy of prostate cancer fails.Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention.Androgen receptor regulation of the versican gene through an androgen response element in the proximal promoter.Tumour-derived TGF-beta1 modulates myofibroblast differentiation and promotes HGF/SF-dependent invasion of squamous carcinoma cellsFibroblasts prolong serum prostate-specific antigen decline after androgen deprivation therapy in prostate cancer.TNF signaling mediates an enzalutamide-induced metastatic phenotype of prostate cancer and microenvironment cell co-cultures.Establishment of an invasive prostate cancer model in transgenic rats by intermittent testosterone administration.Conversion of androgen receptor signaling from a growth suppressor in normal prostate epithelial cells to an oncogene in prostate cancer cells involves a gain of function in c-Myc regulation.Evidence of TGF-β1 mediated epithelial-mesenchymal transition in immortalized benign prostatic hyperplasia cells.Reverse crosstalk of TGFβ and PPARβ/δ signaling identified by transcriptional profiling.Capturing tumor complexity in vitro: Comparative analysis of 2D and 3D tumor models for drug discoveryEffect of androgen ablation on prostatic cell differentiation in dogs.Effects and characterization of paracrine factors produced by human prostate stromal cells in bioassays using rat Sertoli cells, LNCaP tumor cells, and cultured prostate epithelial cells.Smooth muscle contraction and growth of stromal cells in the human prostate are both inhibited by the Src family kinase inhibitors, AZM475271 and PP2.The 22Rv1 prostate cancer cell line carries mixed genetic ancestry: Implications for prostate cancer health disparities research using pre-clinical models.CoCl2 Administration to Vascular MSC Cultures as an In Vitro Hypoxic System to Study Stem Cell Survival and Angiogenesis.Inhibition of human prostate smooth muscle contraction by the LIM kinase inhibitors, SR7826 and LIMKi3.
P2860
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P2860
A human prostatic stromal myofibroblast cell line WPMY-1: a model for stromal-epithelial interactions in prostatic neoplasia.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
A human prostatic stromal myof ...... ctions in prostatic neoplasia.
@en
type
label
A human prostatic stromal myof ...... ctions in prostatic neoplasia.
@en
prefLabel
A human prostatic stromal myof ...... ctions in prostatic neoplasia.
@en
P2093
P356
P1433
P1476
A human prostatic stromal myof ...... ctions in prostatic neoplasia.
@en
P2093
Bello-DeOcampo D
Thraves PS
Williams DE
P304
P356
10.1093/CARCIN/20.7.1185
P407
P4510
P577
1999-07-01T00:00:00Z