Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.

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A complete Leishmania donovani reference genome identifies novel genetic variations associated with virulence Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice

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Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.

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2017 nî lūn-bûn

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2017年論文

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Whole genome sequencing of liv ...... bles product characterization.

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Whole genome sequencing of liv ...... bles product characterization.

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Whole genome sequencing of liv ...... bles product characterization.

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Whole genome sequencing of liv ...... bles product characterization.

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Amit Kaul

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Hira L Nakhasi

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John Torcivia

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Lusine Gasparyan

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Nevien Ismail

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Sreenivas Gannavaram

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Vahan Simonyan

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HIVE-hexagon: high-performance, parallelized sequence alignment for next-generation sequencing data analysis

Deletion of ubiquitin fold modifier protein Ufm1 processing peptidase Ufsp in L. donovani abolishes Ufm1 processing and alters pathogenesis

Census-based rapid and accurate metagenome taxonomic profiling

Reversion of Cold-Adapted Live Attenuated Influenza Vaccine into a Pathogenic Virus

High-Performance Integrated Virtual Environment (HIVE) Tools and Applications for Big Data Analysis.

High-performance integrated virtual environment (HIVE): a robust infrastructure for next-generation sequence data analysis.

Biomarkers of safety and immune protection for genetically modified live attenuated leishmania vaccines against visceral leishmaniasis - discovery and implications.

Evaluation of ex vivo human immune response against candidate antigens for a visceral leishmaniasis vaccine

FDA's Activities Supporting Regulatory Application of "Next Gen" Sequencing Technologies.

Leishmania infantum HSP70-II null mutant as candidate vaccine against leishmaniasis: a preliminary evaluation.

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s41598-017-05088-4

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scholarly article

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10.1038/S41598-017-05088-4

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English

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2017-07-05T00:00:00Z

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28680050

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attenuated vaccine

biomarker

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5498541

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Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.

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P2860

P2860

Whole genome sequencing of live attenuated Leishmania donovani parasites reveals novel biomarkers of attenuation and enables product characterization.

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P1476

P2093

P2860

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P31

P356

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P356

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P1476

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P356

P407

P433

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P698

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