Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit.
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CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markersEvaluation of the kinase domain of c-KIT in canine cutaneous mast cell tumors.c-Kit expression, angiogenesis, and grading in canine mast cell tumour: a unique model to study c-Kit driven human malignancies.Canine and human gastrointestinal stromal tumors display similar mutations in c-KIT exon 11.Development of an in vitro model of acquired resistance to toceranib phosphate (Palladia®) in canine mast cell tumor.Possible prognostic and therapeutic significance of c-Kit expression, mast cell count and microvessel density in renal cell carcinoma.Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors.Onco-epidemiology of domestic animals and targeted therapeutic attempts: perspectives on human oncology.Gastrointestinal stromal tumors in a mouse model by targeted mutation of the Kit receptor tyrosine kinase.The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors.Sequencing and G-quadruplex folding of the canine proto-oncogene KIT promoter region: might dog be used as a model for human disease?Genome-Wide Association Study of Golden Retrievers Identifies Germ-Line Risk Factors Predisposing to Mast Cell Tumours.Immunohistochemical evaluation of AKT protein activation in canine mast cell tumoursMast cells and canine mast cell tumours. A review.Identification of the two KIT isoforms and their expression status in canine hemangiosarcomas.Comparative oncology today.Advances in the diagnosis and management of cutaneous mast cell tumours in dogs.Breed-predispositions to cancer in pedigree dogs.Concordance of c-kit mutational status in matched primary and metastatic cutaneous canine mast cell tumors at baselineRoles for deregulated receptor tyrosine kinases and their downstream signaling molecules in hematologic malignancies.Generation and characterization of novel canine malignant mast cell line CL1.Aggressive local therapy combined with systemic chemotherapy provides long-term control in grade II stage 2 canine mast cell tumour: 21 cases (1999-2012).The novel HSP90 inhibitor STA-9090 exhibits activity against Kit-dependent and -independent malignant mast cell tumorsReceptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy.Kinase dysfunction and kinase inhibitors.Naturally occurring cancers in dogs: insights for translational genetics and medicine.The Relevance of CD117-Immunocytochemistry Staining Patterns to Mutational Exon-11 in c-kit Detected by PCR from Fine-Needle Aspirated Canine Mast Cell Tumor Cells.Expression of Phosphorylated KIT in Canine Mast Cell Tumor.Expression of PDGFR-β and Kit in canine anal sac apocrine gland adenocarcinoma using tissue immunohistochemistry.KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells.NI-1: a novel canine mastocytoma model for studying drug resistance and IgER-dependent mast cell activation.Flow cytometric techniques for detection of candidate cancer stem cell subpopulations in canine tumour models.Cutaneous epitheliotropic lymphoma with dual CD3 and c-kit expression in a dog.Biological effect of tyrosine kinase inhibitors on three canine mast cell tumor cell lines with various KIT statuses.AR-42, a novel HDAC inhibitor, exhibits biologic activity against malignant mast cell lines via down-regulation of constitutively activated Kit.Pilot assessment of vascular endothelial growth factor receptors and trafficking pathways in recurrent and metastatic canine subcutaneous mast cell tumours.Detection of c-kit mutations in canine mast cell tumors using fluorescent polyacrylamide gel electrophoresis.Classification of canine nonangiogenic, nonlymphogenic, gastrointestinal sarcomas based on microscopic, immunohistochemical, and molecular characteristics.The use of KIT and tryptase expression patterns as prognostic tools for canine cutaneous mast cell tumors.Identification of KIT activating mutations in paediatric solitary mastocytoma.
P2860
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P2860
Spontaneous canine mast cell tumors express tandem duplications in the proto-oncogene c-kit.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Spontaneous canine mast cell t ...... s in the proto-oncogene c-kit.
@en
type
label
Spontaneous canine mast cell t ...... s in the proto-oncogene c-kit.
@en
prefLabel
Spontaneous canine mast cell t ...... s in the proto-oncogene c-kit.
@en
P2093
P1476
Spontaneous canine mast cell t ...... s in the proto-oncogene c-kit.
@en
P2093
P304
P356
10.1016/S0301-472X(98)00075-7
P577
1999-04-01T00:00:00Z