DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization.
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Glycogen synthase kinase3 beta phosphorylates serine 33 of p53 and activates p53's transcriptional activityThe corepressor mSin3a interacts with the proline-rich domain of p53 and protects p53 from proteasome-mediated degradationActivation of TRAP/mediator subunit TRAP220/Med1 is regulated by mitogen-activated protein kinase-dependent phosphorylationBARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinaseCrosstalk between sumoylation and acetylation regulates p53-dependent chromatin transcription and DNA bindingp53 Activation following Rift Valley fever virus infection contributes to cell death and viral productionTyrosine phosphorylation of Mdm2 by c-Abl: implications for p53 regulationStress-dependent nucleolin mobilization mediated by p53-nucleolin complex formationThe human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sitesChk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitroWISP-1 attenuates p53-mediated apoptosis in response to DNA damage through activation of the Akt kinaseNMR chemical shift and relaxation measurements provide evidence for the coupled folding and binding of the p53 transactivation domainp53 Proteoforms and Intrinsic Disorder: An Illustration of the Protein Structure-Function Continuum ConceptRegulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complexChecking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressorCritical roles for the serine 20, but not the serine 15, phosphorylation site and for the polyproline domain in regulating p53 turnoverPosttranscriptional regulation of p53 and its targets by RNA-binding proteinsPhosphorylation of Ser-20 mediates stabilization of human p53 in response to DNA damageNucleolar protein GLTSCR2 stabilizes p53 in response to ribosomal stressesAkt3 is responsible for the survival and proliferation of embryonic stem cellsCombination of NTP with cetuximab inhibited invasion/migration of cetuximab-resistant OSCC cells: Involvement of NF-κB signaling.Oxaliplatin responses in colorectal cancer cells are modulated by CHK2 kinase inhibitors.Kinetics of p53 binding to promoter sites in vivo.Molecular interaction map of the mammalian cell cycle control and DNA repair systems.p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.ATM: a mediator of multiple responses to genotoxic stress.Regulation of p53 stability.p53 regulation by post-translational modification and nuclear retention in response to diverse stresses.Mechanisms of switching on p53: a role for covalent modification?The human vaccinia-related kinase 1 (VRK1) phosphorylates threonine-18 within the mdm-2 binding site of the p53 tumour suppressor protein.Stimulation of p53 DNA binding by c-Abl requires the p53 C terminus and tetramerization.Stress signals utilize multiple pathways to stabilize p53Inactivation of p53 by human T-cell lymphotropic virus type 1 Tax requires activation of the NF-kappaB pathway and is dependent on p53 phosphorylation.Jun NH2-terminal kinase phosphorylation of p53 on Thr-81 is important for p53 stabilization and transcriptional activities in response to stress.Dial 9-1-1 for p53: mechanisms of p53 activation by cellular stressRegulation of p53 by hypoxia: dissociation of transcriptional repression and apoptosis from p53-dependent transactivation.DNA damage-induced apoptosis requires the DNA-dependent protein kinase, and is mediated by the latent population of p53.Mutation of mouse p53 Ser23 and the response to DNA damage.Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner
P2860
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P2860
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
DNA damage-inducible phosphory ...... r20, requires tetramerization.
@en
type
label
DNA damage-inducible phosphory ...... r20, requires tetramerization.
@en
prefLabel
DNA damage-inducible phosphory ...... r20, requires tetramerization.
@en
P2093
P2860
P356
P1433
P1476
DNA damage-inducible phosphory ...... r20, requires tetramerization.
@en
P2093
P2860
P304
P356
10.1093/EMBOJ/18.7.1815
P407
P577
1999-04-01T00:00:00Z