Cyclic GMP-dependent protein kinase activates cloned BKCa channels expressed in mammalian cells by direct phosphorylation at serine 1072.
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Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle DisordersStructural analysis of the GLUT1 facilitative glucose transporter (review).Unique aspects of the developing lung circulation: structural development and regulation of vasomotor toneRole of hbeta1 in activation of human mesangial BK channels by cGMP kinaseIRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinaseTREK-1 regulation by nitric oxide and cGMP-dependent protein kinase. An essential role in smooth muscle inhibitory neurotransmissionH2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation.Endothelial cell protein kinase G inhibits release of EDHF through a PKG-sensitive cation channel.Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression.Enhanced K(+) secretion in dextran sulfate-induced colitis reflects upregulation of large conductance apical K(+) channels (BK; Kcnma1)Carbon monoxide--physiology, detection and controlled release.Dual role of protein kinase C on BK channel regulation.Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta.Potassium channels in gastrointestinal smooth muscle.cGMP-dependent protein kinases and cGMP phosphodiesterases in nitric oxide and cGMP action.Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG.Large conductance voltage- and Ca2+-gated potassium (BK) channel β4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases.ABCD of the phosphodiesterase family: interaction and differential activity in COPDImpact of heme and heme degradation products on vascular diameter in mouse visual cortexInteractions between the leucine-zipper motif of cGMP-dependent protein kinase and the C-terminal region of the targeting subunit of myosin light chain phosphataseSodium (2-sulfonatoethyl) methanethiosulfonate prevents S-nitroso-L-cysteine activation of Ca2+-activated K+ (BKCa) channels in myocytes of the guinea-pig taenia caecaCigarette Smoke-Induced Emphysema and Pulmonary Hypertension Can Be Prevented by Phosphodiesterase 4 and 5 Inhibition in MiceM2 muscarinic receptors induce airway smooth muscle activation via a dual, Gbetagamma-mediated inhibition of large conductance Ca2+-activated K+ channel activity.The biology of cyclic GMP-dependent protein kinases.Angiotensin II stimulates internalization and degradation of arterial myocyte plasma membrane BK channels to induce vasoconstriction.Activation of the cGMP/Protein Kinase G Pathway by Nitric Oxide Can Decrease TRPV1 Activity in Cultured Rat Dorsal Root Ganglion Neurons.Cyclic GMP and protein kinase-G in myocardial ischaemia-reperfusion: opportunities and obstacles for survival signaling.Dependence of the excitability of pituitary cells on cyclic nucleotidesEndothelium-Independent Hypoxic Contraction Is Prevented Specifically by Nitroglycerin via Inhibition of Akt Kinase in Porcine Coronary Artery.Hypoxic depression of PKG-mediated inhibition of serotonergic contraction in ovine carotid arteries.Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity.The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failureModulation of BKCa channel gating by endogenous signaling molecules.Mutation of protein kinase C phosphorylation site S1076 on alpha-subunits affects BK(Ca) channel activity in HEK-293 cells.Pressure-induced oxidative activation of PKG enables vasoregulation by Ca2+ sparks and BK channels.Hydrogen sulfide regulates Ca(2+) homeostasis mediated by concomitantly produced nitric oxide via a novel synergistic pathway in exocrine pancreas.Reduction of large-conductance Ca²(+) -activated K(+) channel with compensatory increase of nitric oxide in insulin resistant rats.cGMP-dependent protein kinases as potential targets for colon cancer prevention and treatment.Modulatory Role of Nitric Oxide/cGMP System in Endothelin-1-Induced Signaling Responses in Vascular Smooth Muscle CellsRegulation of cardiovascular TRP channel functions along the NO-cGMP-PKG axis.
P2860
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P2860
Cyclic GMP-dependent protein kinase activates cloned BKCa channels expressed in mammalian cells by direct phosphorylation at serine 1072.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Cyclic GMP-dependent protein k ...... hosphorylation at serine 1072.
@en
type
label
Cyclic GMP-dependent protein k ...... hosphorylation at serine 1072.
@en
prefLabel
Cyclic GMP-dependent protein k ...... hosphorylation at serine 1072.
@en
P2093
P50
P356
P1476
Cyclic GMP-dependent protein k ...... hosphorylation at serine 1072.
@en
P2093
P304
10927-10935
P356
10.1074/JBC.274.16.10927
P407
P577
1999-04-01T00:00:00Z