Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
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The cilia-regulated proteasome and its role in the development of ciliopathies and cancerCilia in autophagy and cancerCurrent topics of functional links between primary cilia and cell cycleNephronophthisis-associated CEP164 regulates cell cycle progression, apoptosis and epithelial-to-mesenchymal transitionThe IN/OUT assay: a new tool to study ciliogenesisMeasuring the primary cilium length: improved method for unbiased high-throughput analysis.Advances in Skeletal Dysplasia GeneticsScreening and functional analysis of a differential protein profile of human breast cancerLoss of primary cilia occurs early in breast cancer development.β-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma.Dido mutations trigger perinatal death and generate brain abnormalities and behavioral alterations in surviving adult mice.Primary cilium suppression by SREBP1c involves distortion of vesicular trafficking by PLA2G3.A conserved role for Notch signaling in priming the cellular response to Shh through ciliary localisation of the key Shh transducer Smo.DNA replication stress underlies renal phenotypes in CEP290-associated Joubert syndromeEpithelial to Stromal Re-Distribution of Primary Cilia during Pancreatic Carcinogenesis.Anoctamin 6 is localized in the primary cilium of renal tubular cells and is involved in apoptosis-dependent cyst lumen formation.A luminescent lanthanide approach towards direct visualization of primary cilia in living cells.Unilateral nephrectomy elongates primary cilia in the remaining kidney via reactive oxygen species.The SYSCILIA gold standard (SCGSv1) of known ciliary components and its applications within a systems biology consortiumUnexpected Roles for Ciliary Kinesins and Intraflagellar Transport Proteins.Gated entry into the ciliary compartment.The ciliary GTPase Arl13b regulates cell migration and cell cycle progressionMKS1 regulates ciliary INPP5E levels in Joubert syndrome.Primary cilia and dendritic spines: different but similar signaling compartments.Drosophila sensory cilia lacking MKS proteins exhibit striking defects in development but only subtle defects in adults.A ternary complex comprising transportin1, Rab8 and the ciliary targeting signal directs proteins to ciliary membranes.The snRNA-processing complex, Integrator, is required for ciliogenesis and dynein recruitment to the nuclear envelope via distinct mechanisms.Rare disruptive mutations in ciliary function genes contribute to testicular cancer susceptibility.Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model.Nephronophthisis: should we target cysts or fibrosis?Ciliopathies - from rare inherited cystic kidney diseases to basic cellular function.Sclt1 deficiency causes cystic kidney by activating ERK and STAT3 signaling.Disruption of KIF3A in patient-derived glioblastoma cells: effects on ciliogenesis, hedgehog sensitivity, and tumorigenesis.Screen-based identification and validation of four new ion channels as regulators of renal ciliogenesisInflammation and Fibrosis in Polycystic Kidney Disease.Permeability barriers for generating a unique ciliary protein and lipid composition.The daughter centriole controls ciliogenesis by regulating Neurl-4 localization at the centrosome.Ionizing radiation increases primary cilia incidence and induces multiciliation in C2C12 myoblasts.Functional Study of the Primary Cilia in ADPKD.Chronic pancreatitis and lipomatosis are associated with defective function of ciliary genes in pancreatic ductal cells.
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Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
2013年论文
@zh
2013年论文
@zh-cn
name
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
@en
type
label
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
@en
prefLabel
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
@en
P2860
P356
P1433
P1476
Functional aspects of primary cilia in signaling, cell cycle and tumorigenesis.
@en
P2093
Rachel H Giles
Sander G Basten
P2860
P2888
P356
10.1186/2046-2530-2-6
P577
2013-04-29T00:00:00Z
P5875
P6179
1023311273